We hypothesize that frequent remote monitoring of blood pressure and real-time antihypertensive medication titration will optimize pregnancy outcomes in a clinically meaningful and cost-effective manner compared to the current standard of care. Therefore, this pilot study, as part of the K12 training support, will evaluate the feasibility of a randomized clinical trial to treat mild chronic hypertension with medication therapy to a blood pressure goal of less than 140/90 mmHg based on remote daily patient monitoring compared to in-office blood pressure readings.
Age 18 or older
Patients with a viable pregnancy <23 weeks of gestation
Chronic hypertension is defined as: 1) Currently receiving treatment for hypertensive disorders OR 2) Newly diagnosed or untreated chronic hypertension is defined as systolic blood pressure >=140 mm Hg or diastolic blood pressure >=90 mm Hg prior to 20 weeks of gestation
Viable pregnancy <23 weeks of gestation
Known secondary cause of hypertension
Known major fetal anomaly
Known fetal demise
Suspected fetal growth restriction
Rutgers, The State University of New Jersey
Lead sponsor
National Center for Advancing Translational Sciences (NCATS)
Collaborator