RePer-AGE: Reorganization of Visuo-cognitive Functions Based on Peripheral Vision With Aging

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-85
SponsorUniversity Hospital, Grenoble

About this trial

The RePer-AGE study investigates how central and peripheral vision contribute to visual recognition and how these mechanisms change with normal aging. The study is based on the hypothesis that peripheral vision provides rapid global information that supports visual recognition through predictive mechanisms. Healthy young adults (18-30 years) and older adults (60-85 years) will undergo visual psychophysical testing, ophthalmological examinations, and, for a subset of participants, functional magnetic resonance imaging (fMRI). The results are expected to improve our understanding of age-related changes in visuo-cognitive functions and provide reference data for future studies on age-related visual disorders.

Eligibility criteria

Qualifiers

Healthy young adults aged 18 to 30 years or healthy older adults aged 60 to 85 years.

Normal or corrected-to-normal visual acuity.

No ophthalmological disease affecting visual function.

For participants aged 60 years or older: Mini-Mental State Examination (MMSE) score ≥23.

Disqualifiers

None

Trial design

Treatments tested in this trial

  • Psychophysical visual recognition tasks
  • Ophthalmological assessment
  • Functional magnetic resonance imaging (fMRI)

Treatment groups

160 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University Hospital, Grenoble

Lead sponsor

Centre National de la Recherche Scientifique, France

Collaborator

University Grenoble Alps

Collaborator

National Research Agency, France

Collaborator