Reproductive Prognosis in Women Seeking Offspring After Medical or Surgical Therapy for Endometriosis

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18-40
SponsorFondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

About this trial

The study aims to compare the percentage of women with endometriosis who undergo PMA after medical vs surgical treatment and to describe conception patterns, pregnancy rates, and number of live vessels in women seeking offspring with endometriosis.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

age <40 years at the time of offspring research

previous ultrasound or surgical diagnosis of endometriosis made in one of the endometriosis referral centres participating in the study

search for offspring after diagnosis

consent to the use of pseudonymised data for research purposes.

Disqualifiers

women without endometriosis

age >=40 years at the time of the search for offspring

women who have undergone demolition surgery

women who do not wish to have offspring

Trial population

Women with endometriosis with an ultrasound or surgical diagnosis of endometriosis in one of the centres participating in the study who sought a pregnancy after diagnosis at an age of less than 40 years. The number of patients required will be approximately 650 in order to detect an absolute difference of ≥10% between the two groups ( medical or surgery terapy)..

Trial design

Design model

Cohort

Time perspective

Retrospective

Treatments tested in this trial

  • PMA

    Other intervention

    use of Medically assisted procreation techniques (PMA)

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

1

endometriosis and PMA

Compare the number of women who undergo PMA after medical treatment with those who undergo PMA after surgery, then compare these data with those reported in the literature

Time frame
2012 to 2021 diagnosis

Secondary outcomes

Other outcomes

Sponsors and contacts

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