Rhomboid Intercostal Sub-serratus Plane Block Versus External Oblique Intercostal Block in Open Nephrectomy

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorCairo University

About this trial

This study aims to compare time of first request of analgesia among patients undergoing rhomboid intercostal sub-serratus plane block versus external oblique intercostal block for perioperative pain management in open nephrectomy.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Both sexes.

American Society of Anesthesiologists (ASA) physical status II, III.

Body mass index (BMI): > 20 kg/ m2 and < 35 kg/ m2.

Patients undergoing open nephrectomy.

Disqualifiers

Patient refusal.

BMI <20 kg/m2 and >35 kg/m2

Known sensitivity or contraindication to drug used in the study (local anesthetics, opioids).

History of psychiatric and cognitive disorders or chronic pain.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Rhomboid intercostal subserratus plane block

    Other intervention

    Patients will receive the rhomboid intercostal subserratus plane block.

  • External oblique intercostal block

    Other intervention

    Patients will receive the external oblique intercostal block.

  • Intravenous morphine

    Drug

    Patients will not receive any interventions (Intravenous morphine 0.1mg/kg after induction of general anesthesia).

Treatment groups

90 Participants
are divided into 3 treatment groups
Group A: Group (A)Experimental treatment 1 intervention
Group B: Group (B)Experimental treatment 1 intervention
Group C: Control groupActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Time of first request of analgesia

Time of first request of analgesia will be recorded from the end of surgery till first dose of morphine administrated.

Time frame
24 hours postoperatively

Secondary outcomes

1

Heart rate

Heart rate will be noted immediately on arrival and at 0, 4, 8, 12, 18 and 24 h postoperatively.

Time frame
24 hours postoperatively
2

Mean arterial blood pressure

Mean arterial blood pressure will be noted immediately on arrival and at 0, 4, 8, 12, 18 and 24 h postoperatively.

Time frame
24 hours postoperatively
3

Total amount of fentanyl

Fentanyl 0.5 μg / kg will be given in case of heart rate or mean arterial blood pressure ≥ 20% of the baseline

Time frame
24 hours postoperatively
4

Total morphine consumption

Intravenous morphine (3 mg) will be provided as rescue of analgesia. The total amount of morphine given in 24 h will be recorded.

Time frame
24 hours postoperatively

Other outcomes

Sponsors and contacts

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