Right Ventricular Strain in Detecting Subclinical Right Ventricular Systolic Dysfunction in Psoriatic Arthritis Patients: Relation to Serum Endostatin Level

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age20-50
SponsorAin Shams University

About this trial

The aim is to assess early right ventricular systolic dysfunction in psoriatic arthritis patients using RV strain echocardiography

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Psoriatic arthritis patients according to CASPAR criteria

Psoriatic arthritis patients without overt cardiovascular symptoms

Patients with age between 20 to 50 years of age

Disqualifiers

Other systemic autoimmune diseases

Patients with a history of known valvular disease, atrial fibrillation or any other arrhythmia , heart failure, ischemic cardiomyopathy severe obstructive pulmonary diseases and metabolic syndrome.

Patients with medical disorders as renal, congenital heart diseases, hematological disorders and cancer patients.

Patients taking certain drugs that have been confirmed to be risk factors for PAH such as appetite suppressant intake drugs (aminorex, fenfluramine derivatives and benfluorex) and chemotherapeutic agents.

Trial population

30 patients with PsA and 30 matched healthy controls

Trial design

Design model

Case-control

Time perspective

Cross-sectional

Treatments tested in this trial

Not listed

Trial groups

60 Participants
are grouped into 2 trial groups
Group A: Control
Group B: Cases of Psoriatic arthritis patients

Trial outcomes

Primary outcomes

1

Detecting subclinical right ventricular systolic dysfunction in PsA patients

Detecting subclinical right ventricular systolic dysfunction in PsA using 2D strain transthoracic echo and its relation to serum endostatin level

Time frame
Up to 24 months

Secondary outcomes

Other outcomes

Sponsors and contacts

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This trial is not recruiting at the moment. You can still explore other options: