About this trial
The aim is to assess early right ventricular systolic dysfunction in psoriatic arthritis patients using RV strain echocardiography
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Psoriatic arthritis patients according to CASPAR criteria
Psoriatic arthritis patients without overt cardiovascular symptoms
Patients with age between 20 to 50 years of age
Disqualifiers
Other systemic autoimmune diseases
Patients with a history of known valvular disease, atrial fibrillation or any other arrhythmia , heart failure, ischemic cardiomyopathy severe obstructive pulmonary diseases and metabolic syndrome.
Patients with medical disorders as renal, congenital heart diseases, hematological disorders and cancer patients.
Patients taking certain drugs that have been confirmed to be risk factors for PAH such as appetite suppressant intake drugs (aminorex, fenfluramine derivatives and benfluorex) and chemotherapeutic agents.
Trial population
30 patients with PsA and 30 matched healthy controls
Trial design
Case-control
Cross-sectional
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Detecting subclinical right ventricular systolic dysfunction in PsA patients
Detecting subclinical right ventricular systolic dysfunction in PsA using 2D strain transthoracic echo and its relation to serum endostatin level
Sponsors and contacts
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This trial is not recruiting at the moment. You can still explore other options: