Role of Magnetic Resonance Imaging in Diagnosis of Adnexal Cystic Lesions

ConditionAdnexal Lesion

Trial statusNot yet recruiting

Trial phaseNot listed

Trial typeObservational

Biological sexFemale

AgeNot listed

SponsorSohag University

About this trial

This prospective study aims to evaluate the diagnostic accuracy of magnetic resonance imaging (MRI) in characterizing adnexal cystic lesions and differentiating benign from malignant lesions. MRI findings will be correlated with histopathology, surgical data, laboratory results, or follow-up imaging when surgery is not performed, to improve diagnostic confidence and guide appropriate patient management.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Female patients of any age with adnexal cystic lesions detected by ultrasound

Adnexal lesions that are indeterminate or suspicious on ultrasound

Patients who provide written and oral informed consent

Disqualifiers

Patients unwilling to participate or complete the study

Contraindications to MRI, including claustrophobia, metallic implants, pacemaker, or prosthetic heart valves

Trial population

The study population will consist of 50 female patients of all ages presenting to the Radiology Department at Sohag University Hospital with adnexal cystic lesions detected on ultrasound. Eligible participants are those with indeterminate or suspicious ultrasound findings requiring further characterization with MRI. Patients will provide written and oral informed consent prior to inclusion.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Magnetic Resonance Imaging
Diagnostic test
Magnetic resonance imaging (MRI) of the pelvis will be performed using 1.5T or 3T scanners with a phased-array pelvic coil. The protocol will include axial, sagittal, and coronal T2-weighted images, axial T1-weighted and fat-suppressed T1-weighted images, diffusion-weighted imaging with ADC maps, and dynamic contrast-enhanced sequences when clinically indicated and not contraindicated.

Treatment groups

50 Participants

are divided into 1 treatment group

Group A: adnexal cystic lesions cohort1 intervention

Trial outcomes

Primary outcomes

Diagnostic accuracy of MRI in characterization of adnexal cystic lesions

Assessment of the diagnostic performance of magnetic resonance imaging (MRI) in differentiating benign from malignant adnexal cystic lesions, using histopathology, intraoperative findings, or follow-up imaging as the reference standard. Diagnostic accuracy will be expressed in terms of sensitivity, specificity, and predictive values.

Time frame

From MRI examination until final diagnosis (surgery, histopathology, or follow-up imaging), up to 6 months

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Sohag University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: