Safety of Low PEEP Maneuvers During ARDS Management
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorCentre Hospitalier Universitaire, Amiens
About this trial
Acute Respiratory distress syndrome (ARDS) is a severe condition in which protective ventilation is a critical point in its management. Positive end expiratory pressure (PEEP) setting can be challenging for clinicians and high PEEP has been associated with better outcome in moderate and severe ARDS. Recently, recruitment to inflation ratio and airway closure have been investigated in order to help PEEP adjustment. However, ventilatory maneuvers are performed with a low level of PEEP and therefore expose to derecruitment and oxygen desaturation. So far, the risk of oxygen desaturation has not been investigated and risk factors are unknown.
The aim of this study is to evaluate the prevalence of oxygen desaturation during ventilatory maneuvers at low level of PEEP in patients with moderate or severe ARDS
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
age : > 18 yo
inclusion criteria: ARDS, Mechanical ventilation, low PEEP maneuvers
Disqualifiers
refusal to participate
Trial population
PEEP in patients with moderate or severe ARDS
Trial design
Design model
Case-only
Time perspective
Retrospective
Treatments tested in this trial
Not listed
Trial groups
No trial groups listed
Trial outcomes
Primary outcomes
1
prevalence of oxygen desaturation
Time frame
24 monthsSponsors and contacts
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Centre Hospitalier Universitaire, Amiens
Lead sponsor
Centre Hospitalier VALENCIENNES
Collaborator
Source ClinicalTrials.gov