Salivary Cytokines, MMP-8 and Dental Caries in Osteoporosis Patients
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age45-75
SponsorAfyonkarahisar Health Sciences University
About this trial
This study examines saliva samples from patients with osteoporosis. The levels of cytokines and Matrix Metalloproteinase-8 (MMP-8) enzyme in saliva will be measured. Additionally, the dental caries status of participants will be evaluated. The aim of this study is to understand the relationship between osteoporosis and oral health. Only saliva samples will be collected from participants; no treatment or medication will be administered.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Willing to give voluntary consent For Group 1, having been diagnosed with osteoporosis For Group 2, being systemically healthy and not having a diagnosis of osteoporosis/osteopenia
Disqualifiers
Having a chronic inflammatory or autoimmune disease Using glucocorticoids, anti-anxiety medications, antidepressants, or antiepileptic drugs Having been diagnosed with any malignancy Having any endocrine disease Having undergone periodontal treatment within the last 6 months
Trial population
Patients diagnosed with osteoporosis who applied to the outpatient clinic. Saliva samples and dental caries status will be evaluated. Participants will be selected according to inclusion and exclusion criteria.
Trial design
Design model
Case-control
Time perspective
Cross-sectional
Treatments tested in this trial
Not listed
Trial groups
50 Participants
are grouped into 2 trial groupsGroup A: Osteoporosis Group
Group B: Control Group
Trial outcomes
Primary outcomes
1
Salivary Cytokine Levels
Measurement of cytokine levels in saliva samples collected from osteoporosis patients
Time frame
day 1Locations
Sponsors and contacts
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Source ClinicalTrials.gov
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