SCREENING AFTER STROKE - ATRIAL FIBRILLATION
ConditionAtrial Fibrillation (AF)
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorVestre Viken Hospital Trust
About this trial
As much as 20-30% of all strokes are attributed to atrial fibrillation (AF), making the detection of AF highly important, as AF-related strokes are largely preventable with optimal treatment. Therefore, most guidelines recommend screening patients for AF after a stroke, although the optimal timing and choice of monitoring device for screening remain undefined. Our aim is to investigate whether AF screening as early as possible after stroke symptom onset provides a higher detection rate compared to screening after discharge. Additionally, we aim to determine if a 3-lead ECG device provides a higher detection rate compared to a 1-lead patch recorder.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
18 years or older
Ischemic stroke
Without known AF or those with previously diagnosed paroxysmal AF exhibiting sinus rhythm upon admission
Disqualifiers
AF at hosptial admission
Unable or unwilling to provide informed consent
A life expectancy of less than one year
Trial population
The design involves a prospective observational trial of an unselected cohort of patients admitted with acute stroke to Bærum Hospital.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
410 Participants
are grouped into 1 trial groupGroup A: Acute ischemic stroke
Trial outcomes
Primary outcomes
1
Impact of timing: Atrial fibrillation detection rate
Detection rate of AF during initial in-hospital screening compared to detection rate during the second screening period starting at hospital discharge (ambulatory)
Time frame
48 to 96 hoursSecondary outcomes
1
Impact of device: Atrial fibrilation detection rate in 1-lead vs. 3-lead ECG recorder
Will a 3-lead ECG device provide a higher detection rate compared to a 1-lead patch recorder when both devices are used in parallel on the same person
Time frame
48 hours2
Impact of Continuity: Atrial fibrillation detection rate in continuous vs. intermittent ECG monitoring
Will 48-hour continuous ECG monitoring provide a higher AF detection rate compared to intermittent AF screening using a handheld thumb ECG performed three times daily for 30 seconds over three consecutive days during the hospital stay.
Time frame
72 hoursLocations
1Map coordinates are unavailable for these locations. Locations are shown below instead.
Vestre Viken Hospital trust, Baerum HospitalRecruiting1346, Sogneprest Munthe-kaas Vei 100, Gjettum
Norway
NorwaySponsors and contacts
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Source ClinicalTrials.gov