Sensory Anesthesia Achieved Through Different Paravertebral Block Approaches for Post-Op Pain Management After VATS Lung Resection

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorCentre hospitalier de l'Université de Montréal (CHUM)

About this trial

Video-assisted thoracoscopic lung resection (VATS) is a minimally invasive surgical approach frequently used in the treatment of lung cancers. The most commonly used analgesic technique for this surgery is the paravertebral block with a single peroperative injection of local anesthetic. However, a recent study conducted at our institution revealed that this approach provided less relief than expected in some patients. In light of these results, it becomes crucial to distinguish between technical failures (absence of sensitive anesthesia) and the intrinsic limits of the chosen regional analgesia technique (pain originating from an unanesthetized area or pain despite the presence of sensitive anesthesia) in order to better relieve patients.

This study aims to objectively assess the areas of anesthesia obtained through three methods of paravertebral block to evaluate their respective performance and optimize post-VATS analgesic management.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients aged 18 years and older

American Society of Anesthesiologists (ASA) score 1-3

Disqualifiers

Contraindication to the paravertebral block (coagulopathy, use of anticoagulants or antiplatelet agents other than aspirin that have not been stopped according to hospital guidelines, thoracoscopic visualization of the paravertebral space expected to be difficult or impossible, anterior spinal surgery with potential discontinuity of the paravertebral space)

Epidural analgesia preferred (high risk of thoracotomy, marginal lung function)

Surgical criteria: conversion to thoracotomy necessary and thoracic epidural or other form of regional analgesia implemented post-operatively

Known allergy to local anesthetics

Trial population

Patients scheduled for elective anatomical pulmonary resection by VATS at two institutions

Trial design

Design model

Other

Time perspective

Prospective

Treatments tested in this trial

  • Evaluation of the hypoesthesia of the thorax

    Other intervention

    In the recovery room, a member of the research team will come to assess the presence of hypoesthesia (loss of sensation) of the thorax using ice and a Von Frey filament applied at three different sections: midscapular, midaxillary and midclavicular.

Treatment groups

90 Participants
are divided into 1 treatment group
Group A: Paravertebral block using percutaneous, transpleural or ultrasound guidance technique1 intervention

Trial outcomes

Primary outcomes

1

Success rate of the sensory block

The success rate of the sensory block, defined as a hypoesthetic level to ice or the Von Frey filament of at least T3 to T8 in the recovery room, assessed at mid-scapular, mid-axillary, and mid-clavicular.

Time frame
One hour after the surgery

Secondary outcomes

1

Severity of acute postoperative pain

The severity of acute postoperative pain according to the visual analog scale for pain (VAS, 0 to 100 mm, where 0 means "no pain" and 100 means the "worst possible pain.") at rest and during coughing, at the thorax 1 hour after surgery.

Time frame
One hour after the surgery
2

Postoperative morphine-equivalents consumption

The total amount of morphine equivalents received perioperatively, including pre-emergence and recovery room doses.

Time frame
Perioperative
3

Total duration in the operating room

Total lenght of stay of the patient in the operating room

Time frame
At the end of the surgery
4

Time to recovery room discharge

The time before reaching the discharge criteria for the patient to leave the recovery room

Time frame
24 hours

Other outcomes

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