Health TrialsbyHealthPanel

Sex Hormones, Postoperative Pain and Opioid Use

ConditionsPostoperative PainOpioid Use
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age11-16
SponsorWashington University School of Medicine

About this trial

Aim 1- To identify relationships between sex hormone levels and postoperative pain and opioid use.

Aim 2: To determine whether the effects of testosterone on postoperative pain and opioid use are mediated by immune factors

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

None

Trial population

Pediatric female patients between the ages 11-16 undergoing an orthopedic surgical procedure

Trial design

Design model

Case-only

Time perspective

Prospective

Treatments tested in this trial

  • Pain

    Behavioral

    Postoperative pain levels

  • Opioid use

    Behavioral

    Postoperative opioid use

Treatment groups

210 Participants
are divided into 1 treatment group
Group A: Postoperative patients2 interventions

Trial outcomes

Primary outcomes

1

Sex hormone level of Testosterone

Time frame
Baseline
2

Sex hormone level of estrogen

Time frame
Baseline
3

Sex hormone level of progesterone

Time frame
Baseline
4

Levels of IL-10 and IL-6

Immune factors

Time frame
Baseline

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Washington University School of Medicine

Lead sponsor

Source ClinicalTrials.gov
Apply now