Socket Preservation Using Autogenous Dentin

ConditionTooth Extraction Site Healing

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18-70

SponsorUniversity of Ostrava

About this trial

Tooth extraction leads to a substantial reduction in alveolar bone volume, with up to 25% loss within the first year and up to 40-60% within three years. This prospective randomized clinical study aims to compare four commonly used methods of alveolar ridge preservation, evaluating their effectiveness in maintaining bone volume for later prosthetic or implant rehabilitation. Alveolar dimensions will be measured using calibrated CBCT imaging pre-extraction and at six months post-extraction.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

18-70 years

no active periodontitis

signed informed consent with participation in the study

need for extraction of teeth other than third molars

Disqualifiers

drug or alcohol abuse

ongoing chemotherapy

ongoing radiotherapy

pregnancy

Trial design

Design model

Parallel

Treatments tested in this trial

Tooth extraction left to heal spontaneously
Procedure/Surgery
Wound after the tooth extraction will be secured with a stitch without addition of any augmentation material.
Tooth extraction plus collagen sponge
Procedure/Surgery
Wound after the tooth extraction will be filled with a collagen sponge (Parasorb Cone, Resorba, Germany) and secured with a stitch.
Tooth extraction plus tricalcium phosphate
Procedure/Surgery
Wound after the tooth extraction will be filled with tricalcium phosphate xenograft (Poresorb TCP, Lasak, Czech Republic), covered with a collagen sponge (Parasorb Cone, Resorba, Germany), and secured with a stitch.
Tooth extraction plus autogenous dentin
Procedure/Surgery
Wound after the tooth extraction will be filled with grounded autogenous dentin, covered with a collagen sponge (Parasorb Cone, Resorba, Germany), and secured with a stitch.

Treatment groups

80 Participants

are divided into 4 treatment groups

Group A: Spontaneous healing secured with a stitch (control group)Active comparator 1 intervention

Group B: Colagen spongeExperimental treatment 1 intervention

Group C: Tricalcium phosphate xenograftExperimental treatment 1 intervention

Group D: Autogenous dentinExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

Alveolar bone width

Absolute and relative change in the alveolar bone width at 1 mm, 3 mm, and 5 mm below the alveolar crest measured from CBCT imagery.

Time frame

6 months

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of Ostrava

Lead sponsor

University Hospital Ostrava

Collaborator

Private dental practice Jalůvka

Collaborator

Source ClinicalTrials.gov

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