Genetics variants could be involved in atypical non-autoimmune diabetes revealed by ketoacidosis. The objective of this research will be to determine the relationships between the genetic variants already described in known monogenic diabetes or identified as involved in glucose metabolism and its regulation, in insulin signaling pathways or in insulin secretion itself in subjects of African and Indian ancestry with atypical forms of non autoimmune diabetes.
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subjects of African and Indian ancestry with atypical forms of non autoimmune diabetes.
Case-only
Prospective
Not listed
known pathogenic mutations described in monogenic diabetes of the MODY type
pourcentage
new pathogenic mutations identified in genes involved in glucose metabolism and its regulation,
pourcentage
genetic mutations.
présence/absence
association between clinical and biological data and DNAI
odds ration
comparing the genetic data found in African and Indian ancestry population
Results with a significant p-value (p \< 0.05)
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