Stepwise Enteral Nutritional Algorithm and Patient Outcomes in Pediatric Intensive Care Units

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age1-16
SponsorAin Shams University

About this trial

The aim of the study to evaluate the effectiveness and patient's outcome after implementing enteral nutrition algorithm designed to achieve optimal enteral nutrition delivery in the pediatric intensive care unit and to evaluate the effect of implementing this protocol on critically ill patient's individual's outcome.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Critically ill infants and children admitted to the Pediatric Intensive Care Units.

Age range from 1 month to 16 years (specifically males up to 14 years and females up to 16 years).

Disqualifiers

Patients who are discharged or died within 24 hours of admission.

Patients with acute pancreatitis.

Patients with esophageal perforation.

Patients with a known metabolic disorder.

Trial design

Design model

Sequential

Treatments tested in this trial

  • Stepwise Enteral Nutritional Algorithm

    Other intervention

    A standardized, stepwise protocol for the initiation, advancement, and maintenance of enteral nutrition in critically ill children. It includes specific guidelines for caloric targets, managing feeding intolerance (vomiting, diarrhea, distention), and standardized fasting times for procedures to minimize interruptions.

Treatment groups

80 Participants
are divided into 2 treatment groups
Group A: Pre-implementation phase (Standard Care)No intervention 0 interventions
Group B: Post-implementation (Intervention)Experimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Time to reach target energy goals

The duration (measured in days) required for the patient to achieve 100% of their calculated daily caloric target via enteral nutrition. Caloric targets are determined using FAO/WHO/UNU estimated energy requirements or the Schofield equation for sedated/ventilated patients.

Time frame
From date of admission until energy goals are reached, assessed up to 28 days.
2

Number of enteral nutrition interruptions

The total count of episodes where enteral feeding was temporarily or permanently stopped. An interruption is defined as the cessation of feeding for reasons such as hemodynamic instability, medical procedures, or aspiration risk.

Time frame
From date of admission up to 28 days.

Secondary outcomes

1

Length of Pediatric Intensive Care Unit stay

The total duration (in days) a patient remains in the PICU from admission to discharge. This measure is compared between the pre-implementation and post-implementation groups to evaluate if the stepwise nutritional algorithm reduces the length of stay.

Time frame
From date of admission assessed up to 28 days.

Other outcomes

Sponsors and contacts

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