The purpose of the study is to understand the biomechanical properties of septal cartilage as well as the cartilages used in nasal reconstruction and to identify them histologically.
Adult patients who have undergone septoplasty, rhinoseptoplasty, or otoplasty, and in whom excess cartilage was removed during the surgical procedure.
Patient refusal
Adult patients who have undergone septoplasty, rhinoseptoplasty, or otoplasty, and in whom excess cartilage was removed during the surgical procedure. This cartilage, usually destined for disposal as surgical waste, is collected with the patient's consent, in accordance with current ethical and regulatory guidelines.
Cohort
Prospective
Analysis of the biomechanical properties of septal cartilage as well as the cartilages used in nasal reconstruction and their histological identification.
Other interventionAnalysis of the biomechanical properties of septal cartilage as well as the cartilages used in nasal reconstruction and their histological identification.
Structural Histological Features of Septal, Costal, and Auricular Cartilage
Structural analysis of cartilage architecture (e.g., chondrocyte distribution/density, extracellular matrix organization, perichondrium integrity) performed ex vivo on surgical waste tissue samples by histological staining, compared across the three cartilage types. No measurement is performed on participants in vivo.
Young's Modulus of Septal, Costal, and Auricular Cartilage
Young's modulus (MPa) measured ex vivo on cartilage tissue discarded as surgical waste, to generate a biomechanical stiffness mapping by cartilage type. No measurement is performed on participants in vivo.
Young's Modulus of Cartilage by Type, Patient Age, and Sex
Comparison of Young's modulus (MPa) values, measured ex vivo on discarded cartilage samples, stratified by cartilage type, patient age, and sex, to establish biomechanical reference data for future biomaterial development.
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