Study on the Significance of Auricular Clip in Prevention and Treatment of Valvular Heart Disease Atrial Thrombosis

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-75
SponsorSecond Affiliated Hospital of Nanchang University

About this trial

To evaluate the safety and clinical efficacy of left atrial appendage in the prevention of thrombus in patients with valvular heart disease, to improve the product according to clinical conditions, to achieve clinically accurate treatment, and to establish the heart valve, the usefulness and universality of Warfarin's anticoagulant model were verified by the specimen library

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients with valvular heart disease aged between 18 and 75

Valvular heart disease [Cardiovascular Surgery Volume, Clinical Diagnosis and Treatment Guidelines, Chinese Medical Association (2011 edition)]

Preoperative cardiac function grade II-III (NYHA), no operation-related contraindications

Understand the nature of this study, agree to participate in all terms of this study, sign informed consent, agree to accept postoperative treatment plan and follow-up requirements, and cooperate to complete follow-up

Disqualifiers

Patients whose left atrial appendage has been resected or occluded

She had a history of open heart surgery with extensive adhesion of the pericardium

Patients cannot be returned due to other reasons

Failed to reach the end point in clinical trials of other drugs or devices

Trial population

Patients requiring heart valve surgery with atrial fibrillation

Trial design

Design model

Case-control

Time perspective

Other

Treatments tested in this trial

  • atrial appendage clip

    Device

    During cardiac surgery, atrial fibrillation patients were treated with atrial appendage clipping

Treatment groups

118 Participants
are divided into 2 treatment groups
Group A: left atrial appendage clip1 intervention
Group B: Left atrial appendage treated with conventional methods1 intervention

Trial outcomes

Primary outcomes

1

Success rate of auricular clip clipping

Success rate of auricular clip clipping

Time frame
12 months
2

Clinical success rate of auricular clip

Rate of patients without ischemic stroke, TIA, or systemic embolism 12 months after cardiac and auricular clipping

Time frame
12 months

Secondary outcomes

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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