About this trial
Inflammation of the tissue surrounding a dental implant (peri-implantitis or peri-implant mucositis) can lead to implant loss in advanced stages. The AmbiJet system utilizes cold atmospheric plasma (CAP), a physical procedure with a strong antibacterial effect. This clinical trial investigates whether the additional application of cold plasma directly on the patient following conventional mechanical cleaning of the implants is safe, well-tolerated, and resolves inflammation more quickly compared to standard treatment.
Eligibility criteria
Qualifiers
Men or women aged >= 18 and <= 65 years.
For women of childbearing age: a form of contraception recognized by conventional medicine during the study.
Written consent has been obtained from each patient for the study.
Current X-ray of the implant region available (<= 6 months prior to first treatment).
Disqualifiers
Known allergies to materials used in the study (gold, copper, polyimide).
Diabetes (type I or type II), vasculitis, osteoporosis, osteomalacia.
Smokers (>1 cigarette/week).
Use of medications to modulate bone metabolism (e.g., bisphosphonates).
Trial design
Treatments tested in this trial
- AmbiJet cold plasma system
- Standard Mechanical Debridement (S3 Guideline)