The Changes Under Different Accommodation of Anterior Eye and 3D Crystal Reconstruction.

ConditionAccommodation
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age20-80
SponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University

About this trial

Accommodation is defined as a dynamic change in the overall refractive power of the eye during near fixation. Despite extensive investigations, the exact nature of human accommodation remains controversial. And recent alternative theories question the original concept of accommodation.Different experts have put forward different hypotheses. The age-related changes that underlie presbyopia are also not fully understood.Because of these unanswered questions, the topic of regulation and presbyopia remains a focus of research.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

None

Disqualifiers

Patients with other systemic diseases

Patients with a history of eye surgery

Patients with intraocular lens or aphakia

Patients with strabismus and amblyopia

Trial population

Age 20-80 years old; Astigmatism ≤-1.50D; Best corrected visual acuity ≥4.9;Excluding other systemic underlying diseases; Have a history of eye surgery; Patients with intraocular lens or aphakia; Patients with strabismus and amblyopia; Pregnant or lactating women; People with mental disorders or neurological diseases who cannot cooperate with the examination;

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

120 Participants
are grouped into 3 trial groups
Group A: Group A was 20-40 years old
Group B: Group B was 40-60 years old
Group C: Group C was 60-80 years old

Trial outcomes

Primary outcomes

1

Central corneal thickness changes during accommodation

Central corneal thickness CCT(μm)

Time frame
Baseline, after accommodation(30 minutes after using pilocarpine)
2

peripheral corneal thickness changes during accommodation

peripheral corneal thickness(μm)

Time frame
Baseline, after accommodation(30 minutes after using pilocarpine)
3

anterior chamber depth changes during accommodation

anterior chamber depth ACD(mm)

Time frame
Baseline, after accommodation(30 minutes after using pilocarpine)
4

anterior chamber Angle Angle changes during accommodation

anterior chamber Angle Angle ACA(°)

Time frame
Baseline, after accommodation(30 minutes after using pilocarpine)

Secondary outcomes

Other outcomes

Sponsors and contacts

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