The Combined Effect of Mulligan Mobilization, Pain Neuroscience-Based Training, and Core Stabilization Exercises in Frozen Shoulder Patients

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorYeditepe University

About this trial

The purpose of this randomized controlled study is to investigate the effects of a combined rehabilitation program consisting of Mulligan Mobilization with Movement (MWM), Pain Neuroscience Education (PNE), and core stabilization exercises in individuals with adhesive capsulitis (frozen shoulder).

The main questions this study aims to answer are:

Does the combination of Mulligan mobilization, Pain Neuroscience Education, and core stabilization exercises reduce pain in individuals with adhesive capsulitis? Does this combined intervention improve shoulder range of motion, shoulder function, quality of life, scapular dyskinesis, and pain catastrophizing compared with conventional physical therapy?

Participants diagnosed with adhesive capsulitis will be randomly assigned to one of two groups. The intervention group will receive Mulligan mobilization, Pain Neuroscience Education, and core stabilization exercises, while the control group will receive conventional physical therapy, including TENS, hot-pack application, passive joint mobilization, and stretching exercises. Both groups will participate in treatment sessions three times per week for six weeks. Outcome measures will be assessed at baseline and after completion of the 6-week intervention period.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adults aged 18 to 65 years

Diagnosis of adhesive capsulitis confirmed by an orthopedic surgeon or a physical medicine and rehabilitation physician

Presence of shoulder pain and limitation of shoulder range of motion

Ability to communicate verbally

Disqualifiers

MMSE score below 24

Severe cognitive impairment

Severe psychiatric disorders

Active infectious disease

Trial design

Design model

Parallel

Treatments tested in this trial

  • Pain Neuroscience Education (PNE)

    Behavioral

    Participants will receive Pain Neuroscience Education focused on the biopsychosocial nature of pain, central sensitization, the distinction between pain and tissue damage, and strategies to reduce fear of movement. The initial educational session will last approximately 15-20 minutes, followed by 5-10 minute reinforcement sessions throughout the intervention period. Education will be delivered through verbal explanations and interactive discussion.

  • Mulligan Mobilization With Movement (MWM)

    Procedure/Surgery

    Participants will receive Mulligan Mobilization with Movement techniques applied to the glenohumeral joint, including posterolateral glide with active abduction, inferior glide with shoulder flexion, and posterior glide with internal rotation. Mobilizations will be performed within a pain-free range of motion. Each technique will be administered in 3 sets of 10 repetitions with 30 seconds of rest between sets. Treatment will be provided three times per week for six weeks

  • Core Stabilization Exercises

    Behavioral

    Participants will perform Dynamic Neuromuscular Stabilization (DNS)-based core stabilization exercises. The program will include diaphragmatic breathing, supine 90/90 positioning, abdominal bracing, and progression to dead bug, bird-dog, and modified plank exercises as tolerated. Exercises will be performed in 2-3 sets of 8-12 repetitions with 10-20 second isometric holds. Progression will occur from stable to unstable surfaces and from static to dynamic activities

  • Conventional Physical Therapy

    Other intervention

    Participants in the control group will receive conventional physical therapy consisting of transcutaneous electrical nerve stimulation (TENS) applied at a sensory level for 20 minutes, hot-pack application for 20 minutes, passive shoulder joint mobilization exercises, pendulum exercises, and wand exercises. Treatment sessions will be conducted three times per week for six weeks.

Treatment groups

36 Participants
are divided into 2 treatment groups
Group A: Experimental - Combined Treatment GroupExperimental treatment 3 interventions
Group B: Active Comparator - Conventional Physical Therapy GroupActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Pain Intensity

Pain intensity during movement will be assessed using the Visual Analog Scale (VAS). Higher scores indicate greater pain intensity.

Time frame
Baseline and week 6
2

Shoulder Function

Shoulder pain, function, and patient satisfaction will be evaluated using the Penn Shoulder Score (PSS). Higher scores indicate better shoulder function.

Time frame
Baseline and week 6
3

Shoulder Range of Motion

Active shoulder flexion, abduction, internal rotation, and external rotation range of motion will be measured using a goniometer.

Time frame
Baseline and week 6

Secondary outcomes

1

Pain Catastrophizing

Pain-related catastrophic thinking will be assessed using the Pain Catastrophizing Scale (PCS). Higher scores indicate greater pain catastrophizing.

Time frame
Baseline and week 6
2

Core Stability

Core stability and neuromuscular control will be assessed using the Sahrmann Core Stability Test.

Time frame
Baseline and week 6
3

Change in Scapular Dyskinesis

Scapular movement patterns and dyskinesis will be evaluated using the Scapular Dyskinesis Test.

Time frame
Baseline and week 6
4

Change in Health-Related Quality of Life

Health-related quality of life will be assessed using the 12-Item Short Form Health Survey (SF-12).

Time frame
Baseline and week 6

Other outcomes

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