About this trial
In this study, the investigators compared the improvement of liver reserve function related indicators in patients with liver cirrhosis after laparoscopic splenectomy and azygoportal disconnection. To determine whether surgical treatment can help enhance postoperative liver reserve function and improve patient prognosis.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
A clinical, radiological or histologic diagnosis of cirrhosis of any etiology
Splenomegaly with secondary hypersplenism
gastroesophageal variceal bleeding
Informed consent to participate in the study
Disqualifiers
Hepatocellular carcinoma or any other malignancy,
Child-Pugh grade C
Recent peptic ulcer disease
History of Hemorrhagic stroke
Trial design
Single group
Treatments tested in this trial
Laparoscopic splenectomy and azygoportal disconnection
Procedure/SurgeryThe laparoscopic splenectomy and azygoportal disconnection was performed by the same surgical team.
Treatment groups
Trial outcomes
Primary outcomes
Liver reserve function ICG-K at 3 months after surgery.
The level of liver reserve function ICG-K at 3 months after surgery.
Liver reserve function ICG-K at 6 months after surgery.
The level of liver reserve function ICG-K at 6 months after surgery.
Liver reserve function ICG-K at 12 months after surgery.
The level of liver reserve function ICG-K at 12 months after surgery.
Liver reserve function ICG-K at 24 months after surgery.
The level of liver reserve function ICG-K at 24 months after surgery.
Sponsors and contacts
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