About this trial
The goal of this study is to investigate the effect of combining olive leaf extract supplementation with endurance training (moderate intensity continuous training or sprint interval training). We hypothesize that OLE supplementation during training, as compared to training alone with placebo, will translate into better performance outcomes. More specifically, we hypothesize that the additional benefits of OLE supplementation on performance will be mediated by improved mitochondrial characteristics in skeletal muscle and increased neural activation.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Being between 18 and 45 years old
Being healthy (assessed through the PAR-Q questionnaire).
Being physically active, but not involved in any structured training program
Being available for the study period.
Disqualifiers
If a participant answers positively to any YES/NO question in the PAR-Q health questionnaire. For questions requiring a precision, any positive answer will be reviewed by a medical doctor, who will determine the inclusion/exclusion of the participant.
Having allergy to xylocaine
Being pregnant.
Trial design
Parallel
Treatments tested in this trial
Olive leaf extract
Dietary supplementA capsule containing 250 mg of an olive leaf extract preparation will be swallowed with a glass of water daily for 21 days.
Placebo
Dietary supplementA capsule containing 336 mg of cellulose microcrystalline will be swallowed with a glass of water daily for 21 days.
Treatment groups
Trial outcomes
Primary outcomes
maximal aerobic power
maximal power (in watts) measured during a graded exercise to failure
Secondary outcomes
Maximal oxygen uptake
maximal oxygen uptake (ml/min/kg) measured during a graded exercise until failure
Submaximal heart rate and power
heart rate and power measured during submaximal cycling exercise
Knee extensor neuromuscular function
maximal voluntary contraction force and maximal voluntary activation level
Sponsors and contacts
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