About this trial
This study aimed to determine the effects of Opioid-free anesthesia using dexmedetomidine and bilateral Transversus abdominis plane block on the quality of recovery, incidence of Opioid-free anesthesia, and post-operative pain and delirium in morbid obese patients undergoing gynecological surgeries.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
50 female patients aged 21-65 years.
Patients with a Body mass index≥ 35 kg/m2
American society of Anesthesiology class II-III.
Undergoing elective gynecological surgeries.
Disqualifiers
Patient refusal.
History of allergy to local anesthetic.
Liver or renal pathology affecting drug elimination.
Mental dysfunction or cognitive disorders.
Trial design
Parallel
Treatments tested in this trial
Opioid Free Anesthesia
Procedure/Surgerypatients will receive opioid free anesthesia and bilateral ultrasound guided transversus abdominus plane block.
Control group (general anesthesia)
Procedure/Surgerypatients will receive conventional general anesthesia
Treatment groups
Trial outcomes
Primary outcomes
quality of recovery on postoperative day
The Quality of Recovery-40 questionnaire scores. The Quality of Recovery-40 questionnaire includes five dimensions of recovery: physical comfort (12 items), emotional state (9 items), physical independence (5 items), psychological support (7 items), and pain (7 items).
Secondary outcomes
Postoperative pain severity
Postoperative pain severity will be assessed by the numerical rating scale ( 0 no pain while 10 is the maximum pain).
Sponsors and contacts
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