The Effect of Serum Calcium Levels on Postoperative Pain: A Prospective Observational Study

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-70
SponsorThe Second Affiliated Hospital of Chongqing Medical University

About this trial

This is a prospective observational study. To investigate the effect of serum calcium levels on postoperative pain in patients undergoing abdominal surgery, and to determine whether changes in serum calcium levels are a risk factor for postoperative pain.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Aged 18-70 years old

American Society of Anesthesiologists Classification I-III

Patients undergoing elective abdominal surgery under general anesthesia

Patients participate voluntarily and sign an informed consent form

Disqualifiers

Patients with a history of severe disease

Patients with chronic preoperative pain and/or long-term analgesic use

Patients with hearing disorders or verbal communication difficulties

Patients with psychiatric disorders or cognitive dysfunction

Trial population

Patients who underwent elective abdominal surgery under general anesthesia

Trial design

Design model

Other

Time perspective

Prospective

Treatments tested in this trial

  • Peripheral venous blood

    Diagnostic test

    Peripheral venous blood was collected before and after the surgery to measure the total serum calcium levels.

  • Arterial blood

    Diagnostic test

    Arterial blood was collected before anesthesia induction and after removal of the artificial airway to measure ionized calcium levels.

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

1

The incidence of pain NRS score ≥6 within 48 hours after surgery

NRS score: pain was assessed using a 10-point NRS (range: 0-10, 0 and 10 indicate no pain and the most extreme pain imaginable, respectively)

Time frame
From the end of the surgery to 48 hours after surgery

Secondary outcomes

1

The maximum incisional pain score at 0-12h postoperatively

NRS score: pain was assessed using a 10-point NRS (range: 0-10, 0 and 10 indicate no pain and the most extreme pain imaginable, respectively)

Time frame
From the end of the surgery to 12 hours after surgery
2

The maximum incisional pain score at 12-24h postoperatively

NRS score: pain was assessed using a 10-point NRS (range: 0-10, 0 and 10 indicate no pain and the most extreme pain imaginable, respectively)

Time frame
From 12hours to 24 hours after surgery
3

The maximum incisional pain score at 24-48h postoperatively

NRS score: pain was assessed using a 10-point NRS (range: 0-10, 0 and 10 indicate no pain and the most extreme pain imaginable, respectively)

Time frame
From 24 hours to 48 hours after surgery
4

The maximum visceral pain score at 0-12h postoperatively

NRS score: pain was assessed using a 10-point NRS (range: 0-10, 0 and 10 indicate no pain and the most extreme pain imaginable, respectively)

Time frame
From the end of the surgery to 12 hours after surgery

Other outcomes

Sponsors and contacts

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