Health TrialsbyHealthPanel

The Effect of Short-term Bed Rest on Cardiac Function Measured by Cardiac Magnetic Resonance Imaging

ConditionsRestHealthy
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorUniversity of Copenhagen

About this trial

The primary objective of this study is to investigate the effect of short-term bed rest (4 hours) on heart function, measured by cardiac magnetic resonance (CMR), in healthy participants. This aim will be addressed through a single-arm repeated study, assessing participants during three hours of bedrest.

The hypothesis is that short-term bed rest will decrease cardiac output measured by repeated CMR scans.

This study will also investigate the reproducibility of CMR within a narrow time frame. Limited data are available on these aspects, despite their critical importance for conducting consecutive examinations, both in clinical practice and research trials10-12. The study also aims to investigate the appliances of short-time measures of cardiac function.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Age between 18-80 years old.

No use of medications with influence on heart function.

For ethical reasons, we only include participants who are willing to be informed on new health information, as CMR may reveal relevant secondary health findings.

Disqualifiers

Diabetes, kidney, or liver disease.

Contraindications to CMR, e.g., abdominal height exceed limitations of the MR-scanner, pacemaker, aortastent, neurostimulator, or other electronic device implanted, implanted metal devices, severe claustrophobia, or physiological diseases.

Pregnant, lactating, or planning to become pregnant within the study period.

In ongoing cancer treatment.

Trial design

Design model

Single group

Treatments tested in this trial

  • Bedrest

    Other intervention

    Investigation of the effect of short-term bed rest (3 hours) on heart function, measured by cardiac magnetic resonance, in healthy participants ( males and females)

Treatment groups

19 Participants
are divided into 1 treatment group
Group A: Cardiac magnetic resonance measurementsExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

cardiac output

Change in cardiac output will be measured assessed by repeated cardiac magnetic resonance measurement after shortterm bed rest compared with before bedrest.

Time frame
0-4 hours

Secondary outcomes

1

Left ventricular ejection fraction

Left ventricular ejection fraction willl be measured by cardiac magnetic resonance before and after shortterm bedrest

Time frame
0-4 hours

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of Copenhagen

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: