The Effect of Single Lung Ventilation Duration on Postoperative Pulmonary Complications in Thoracic Surgery

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-85
SponsorDr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

About this trial

This observational study investigates the relationship between the duration of single-lung ventilation (SLV) and the incidence of postoperative pulmonary complications (PPCs) such as pneumonia, pneumothorax, hemothorax, acute lung injury, and acute respiratory distress syndrome (ARDS) in adult patients undergoing thoracic surgery. A total of 134 patients aged 18-85 years, scheduled for thoracic surgery requiring SLV, will be monitored. Data including SLV duration, perioperative parameters, and postoperative pulmonary outcomes will be analyzed.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

None

Trial population

The study population will consist of adult patients aged 18 to 85 years who are scheduled to undergo thoracic surgery at Etlik City Hospital and require OLV during the procedure. Patients will be included if they meet the eligibility criteria of being over 18 years old, undergoing thoracic surgery, receiving intraoperative OLV, and providing informed consent to participate in the study. Patients will be excluded if they are part of the pediatric age group, do not require OLV, or decline participation. A total of 134 eligible patients will be prospectively enrolled and followed for seven days postoperatively to assess the occurrence of pulmonary complications.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • One-Lung ventilation

    Procedure/Surgery

    In this observational study, the naturally occurring duration of intraoperative single-lung ventilation (SLV) during thoracic surgery will be recorded. No intervention is applied or modified for research purposes. The exposure of interest is the total duration (in minutes) of SLV, which will be timed from initiation to termination during surgery. This variable will be analyzed in relation to postoperative pulmonary complications.

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

1

Postopertive Pulmonary Complications

Postoperative pulmonary complications (PPCs) are defined as respiratory events occurring within the first seven days following thoracic surgery, which negatively impact patient outcomes. In this study, PPCs include pneumonia, pneumothorax, hemothorax, acute lung injury, acute respiratory distress syndrome (ARDS), prolonged oxygen requirement, unplanned reintubation, and the need for non-invasive ventilation. These complications will be identified through clinical assessment, arterial blood gas analysis, and postoperative imaging such as chest X-rays. Each case will be evaluated using predefined diagnostic criteria to ensure consistency. The incidence of PPCs will be analyzed in relation to the duration of intraoperative single-lung ventilation.

Time frame
postoperative 7 days

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.