The Effects of Pancreatic Enzyme Supplementation in Critically Ill Patients on Enteral Feeding
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorSeoul National University Hospital
About this trial
Determine the effect of high-dose pancreatic enzyme supplementation on nutritional indicators and clinical course in critically ill patients undergoing enteral nutrition.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Adults 19 years and older
Hospitalized in the surgical/medical intensive care unit of the Seoul National University Hospital
Enteral nutrition
Patients who consented to this study
Disqualifiers
chronic pancreatitis
unresectable pancreatic cancer
History of pancreatectomy
Underlying diseases in which the effect of Exocrine pancreatic enzyme administration is difficult to show
Trial design
Design model
Parallel
Treatments tested in this trial
Exocrine Pancreatic Enzyme
DrugPancreatic enzyme supplementation for critically ill patients on enteral nutrition
Placebo
DrugPlacebo of Pancreatic enzyme for critically ill patients on enteral nutrition
Treatment groups
170 Participants
are divided into 2 treatment groupsGroup A: InterventionExperimental treatment 1 intervention
Group B: ControlPlacebo comparator 1 intervention
Trial outcomes
Primary outcomes
1
Change of Phase angle (°)
Change from Baseline Phase angle (°) at 2 weeks or discharge
Time frame
Baseline, 7 days after starting enteral nutrition, 14 days after starting enteral nutritionSecondary outcomes
1
Skeletal Muscle Mass (SMM) (kg)
Skeletal Muscle Mass (SMM) (kg)
Time frame
Baseline, 7 days after starting enteral nutrition, 14 days after starting enteral nutritionSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov