The multicenter Cardiology Monitoring Platform registry (mCMP-registry) is a prospective observational registry including multi-omics (diagnostic) measurements performed as part of routine clinical care, bio-banking (optional), and yearly questionnaires (optional).
It's objective is to optimize (early) diagnosis and risk-stratification of (early) cardiovascular diseases, specifically cardiomyopathy phenotypes, arrhythmias, and coronary artery disease, and to create a better understanding of underlying pathophysiological processes.
Referred to the cardiology or genetic department for heart failure like symptoms (as stated in the ESC 2016 Guidelines(3)) or for cardiac/cardiogenetic screening;
Age ≥16 years.
Unwillingness to participate or unable to give written informed consent (e.g. due to language barriers or severe intellectual disability).
All subjects aged ≥16 years that have been referred to the cardiology or genetics department for cardiac symptoms, cardiac screening or cardiogenetic screening are eligible for inclusion.
Cohort
Prospective
Not listed
(sudden) cardiac death or heart transplantation
Death attributed to a cardiac cause or sudden, or heart transplantation.
Heart Failure hospitalization
Hospitalization due to cardiac decompensation or prolonged hospitalization due to cardiac decompensation
Life-threatening arrhythmias
justified implantable cardioverter-defibrillator shock, justified anti-tachypacing therapy, cardiac arrest, hemodynamic unstable ventricular tachycardia
Quality of life EQ-5D questionnaire
EQ-5D questionnaire
Economic burden
institute for Medical Technology Assessment (iMTA) Productivity Cost Questionnaire (iPCQ) and iMTA Medical Consumption Questionnaire (iMCQ)
Age
Age based on birth date
Sex
Sex (biological)
Body mass index
BMI
Underlying pathogenic
variants found in cardiac associated genes
Click on the lead sponsor to view all of their trials.
Maastricht University Medical Center
Lead sponsor
Zuyderland Medical Centre
Collaborator
