Health TrialsbyHealthPanel

The Use of Diaphragmatic Ultrasonography in Mechanical Ventilation Weaning Decision in COPD Patient

ConditionsUltrasonographyMechanical Ventilation WeaningChronic Obstructive Pulmonary Disease (COPD)
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age21-70
SponsorTanta University

About this trial

The aim of this study is to evaluate the use of diaphragmatic ultrasonography in taking mechanical ventilation weaning decision and predicting outcome in Chronic obstructive pulmonary disease patient.

Primary outcome:

• Number of patients with failed weaning trial and need reintubation.

Secondary outcomes:

* Time till extubation trial. * Ventilation free days after extubation less or more than 48h . * Number of Intensive care unit discharges. * Sensitivity and specificity of diaphragmatic assessment as a predictor of weaning.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adult patient more than 21 years old of both sexes, coming to our intensive care unit with acute exacerbation of Chronic obstructive pulmonary disease & need mechanical ventilation at least 48 hr.

Disqualifiers

Patient refusal.

Morbid obesity with body mass index > 35 kg/m2.

Patients with a history of recent thoracic surgery.

Neuromuscular disorders affecting the diaphragm e.g.(myopathy).

Trial design

Design model

Parallel

Treatments tested in this trial

  • conventional clinical criteria of weaning from mechanical ventilation

    Diagnostic test

    Patients will be weaned after fulfilling the conventional clinical criteria of weaning from mechanical ventilation by using spontaneous breathing trials

  • conventional clinical criteria and ultrasonic criteria for weaning

    Diagnostic test

    Patients will be weaned using the conventional clinical criteria and ultrasonic criteria for weaning.

Treatment groups

140 Participants
are divided into 2 treatment groups
Group A: conventional clinical criteria of weaning from mechanical ventilation by using spontaneous breathingExperimental treatment 1 intervention
Group B: conventional clinical criteria and ultrasonic criteria for weaningExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Number of patients with failed weaning trial

Time frame
28 day

Secondary outcomes

1

Time till extubation trial.

Time frame
28 days
2

Number of Intensive care unit discharges

Time frame
28 days

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Tanta University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: