The Value of Bowel Sounds in Evaluating Postoperative Intestinal Function Recovery in Colorectal Cancer Patients
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-90
SponsorZhongnan Hospital
About this trial
This study enrolls patients scheduled to undergo curative surgery for colorectal cancer. Bowel sounds will be assessed preoperatively and postoperatively. By comparing intraoperative variables, the incidence of perioperative complications, reoperation rates, and postoperative outcomes-including time to first flatus, resumption of oral intake, and occurrence of intestinal obstruction-this study aims to investigate the association between perioperative bowel sounds and postoperative recovery, and provide evidence-based support for the clinical application of bowel sound monitoring.
Supplementary Definitions
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Aged 18-80 years.
Histopathologically confirmed colorectal adenocarcinoma according to the WHO 2022 classification.
No restriction on prior neoadjuvant or other antitumor therapies, including chemotherapy, radiotherapy, targeted therapy, or immunotherapy.
Able to understand the study requirements and voluntarily provide written informed consent (patient and/or legally authorized representative).
Disqualifiers
Severe cardiac dysfunction (NYHA Class III or IV).
Severe hepatic dysfunction (MELD score >12).
Severe renal dysfunction (eGFR <30 mL/min/1.73 m² [CKD stage 4-5] or end-stage renal disease requiring dialysis).
Severe pulmonary dysfunction (resting PaO₂ <60 mmHg on room air or respiratory failure requiring long-term oxygen therapy or mechanical ventilation).
Trial population
This study enrolls patients scheduled to undergo curative surgery for colorectal cancer.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
colorectal surgery
Procedure/SurgeryBased on the preoperative multidisciplinary team (MDT) discussion, the appropriate surgical procedure was selected, including right hemicolectomy, left hemicolectomy, or radical resection for rectal cancer, as clinically indicated.
Treatment groups
172 Participants
are divided into 2 treatment groupsGroup A: normal group1 intervention
Group B: POI group1 intervention
Trial outcomes
Primary outcomes
1
Occurrence of postoperative ileus ( POI) after surgery.
Time frame
From surgery through postoperative day 30Secondary outcomes
1
Postoperative Complications within 30 Days
Incidence of complications such as anastomotic leak/dehiscence, anastomotic bleeding, ischemic bowel necrosis, intra-abdominal infection, intra-abdominal hemorrhage, early postoperative intestinal obstruction, postoperative ileus, pulmonary infection, and other complications, as well as reoperations resulting from these events. The severity of complications will be graded using the Classification of Surgical Complications.
Time frame
From surgery through postoperative day 302
Length of postoperative hospital stay
Length of postoperative hospital stay, defined as the number of days from the date of surgery to the date of hospital discharge. A longer hospital stay indicates delayed postoperative recovery or the occurrence of postoperative complications.
Time frame
From surgery through postoperative day 303
Time to first flatus
Time to first flatus, defined as the time (in hours) from the completion of surgery to the patient's first reported passage of flatus.
Time frame
From surgery through postoperative day 304
Time to first defecation
Time to first defecation, defined as the time (in hours) from the completion of surgery to the patient's first bowel movement
Time frame
From surgery through postoperative day 30Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Zhongnan Hospital
Lead sponsor
Wuhan University
Collaborator
Source ClinicalTrials.gov