The aim is to evaluate the effect of letrozole pretreatment on the induction time during medical evacuation using misoprostol in women diagnosed with missed abortion, and to compare its efficacy and safety to misoprostol alone.
Women aged 18 - 45 years.
Diagnosed with missed abortion confirmed by ultrasound (absent fetal heartbeat and/or no embryonic development).
Gestational age ≤ 12 weeks based on last menstrual period
Hemoglobin levels >10 g/dL.
Incomplete abortion, inevitable abortion, or threatened miscarriage.
Suspected ectopic pregnancy and molar pregnancy.
History of allergy or contraindication to misoprostol or letrozole.
Coagulopathy or use of anticoagulant medications.