Health TrialsbyHealthPanel

Thoracic Epidural Anesthesia Versus Paravertebral Block for Awake Thoracotomy

ConditionsThoracic Epidural AnesthesiaParavertebral BlockAwake Thoracotomy
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorCairo University

About this trial

This study aims to compare paravertebral block and thoracic epidural in awake thoracotomy.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age from 18 to 60 years.

Both genders.

American Society of Anesthesiologists (ASA) physical status classification II or III.

Scheduled for thoracotomy.

Disqualifiers

Poor cardiac function (ejection fraction less than 50%).

Patients with bad pulmonary function testing (PFTs). Absolute contraindication to thoracic epidural anesthesia includes patient refusal, allergy to local anesthetics, coagulopathy, active neurologic disorders, skin infection at the insertion site, uncooperative patients, uncontrolled cough, and unfavorable anatomy for thoracic epidural.

Thoracic spine disorders require chest wall resection or emergency thoracic surgery.

Had a previous thoracotomy (scarring due to prior surgery can limit the effectiveness of paravertebral block, and these patients may have existing chronic pain).

Trial design

Design model

Parallel

Treatments tested in this trial

  • Thoracic epidural block

    Other intervention

    Patients will preoperatively receive an awake thoracic epidural block.

  • Paravertebral block

    Other intervention

    Patients will preoperatively receive a paravertebral block.

Treatment groups

60 Participants
are divided into 2 treatment groups
Group A: Thoracic epidural block groupExperimental treatment 1 intervention
Group B: Paravertebral block groupExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Intraoperative fentanyl consumption

Additional bolus doses of fentanyl 0.5µg/kg will be given if the mean arterial blood pressure or heart rate rises above 20% of baseline levels.

Time frame
Intraoperatively

Secondary outcomes

1

Time to the 1st rescue analgesia

Time to first request of rescue analgesia will be assessed from the end of surgery till first dose of morphine administrated.

Time frame
48 hours postoperatively
2

Mean arterial pressure

Mean arterial pressure will be recorded at baseline, and every 15min till the end of surgery

Time frame
Till the end of surgery (Up to 2 hours)
3

Heart rate

Heart rate will be recorded at baseline, and every 15min till the end of surgery

Time frame
Till the end of surgery (Up to 2 hours)
4

Total morphine consumption

If numeric rating scale (NRS)\>3 at rest will be observed, rescue analgesia via IV morphine 3 mg boluses will be administered.

Time frame
48 hours postoperatively

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Cairo University

Lead sponsor

Source ClinicalTrials.gov
Apply now