TransREctus Sheath PrePeritoneal Procedure (TREPP) for Inguinal Hernia Repair

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorAssiut University

About this trial

Inguinal hernia repair remains one of the most commonly performed surgical procedures worldwide. Tension-free repair with mesh augmentation is the predominant treatment option, either achieved by preperitoneal laparoscopic hernioplasty or Lichtenstein procedure (LP). As the recurrence rate is reduced to less than 5 % after mesh repair, nowadays, long-term morbidity associated with open inguinal hernia repair is mainly related to chronic postoperative inguinal pain (CPIP). Despite many hypotheses about the possible causes for CPIP, there is now consensus that involvement of inguinal nerves plays a major role.

The trans rectus sheath extra-peritoneal procedure (TREPP) is a minimally invasive open approach utilizing the rectus sheath to access the preperitoneal space. It has shown promise in providing effective repair with potential advantages in cosmesis, postoperative pain, and recurrence rates. It is a medial approach avoiding the interference with the course of all (three) inguinal nerves through lateral abdominal wall.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adults with primary unilateral or bilateral inguinal hernia

Disqualifiers

Strangulated hernias.

Severe comorbidities precluding surgery ((ASA Class IV,V)

Trial design

Design model

Single group

Treatments tested in this trial

  • trans rectus sheath extra-peritoneal procedure (TREPP)

    Procedure/Surgery

    The TREPP technique, a minimally invasive open approach utilizing the rectus sheath to access the preperitoneal space

Treatment groups

30 Participants
are divided into 1 treatment group
Group A: TREPP groupExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Recurrence rate

Number and percentage of patients with recurrence of hernia after surgery

Time frame
through study completion, an average of 1 year

Secondary outcomes

1

Incidence of chronic postoperative inguinal pain

Number and percentage of patients with groin pain that lasts more than three months after inguinal hernia surgery

Time frame
3 months after surgery

Other outcomes

Sponsors and contacts

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