Treatment Costs of Kidney Injury in Patients Having Heart Surgery in the UK

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorThe Royal Wolverhampton Hospitals NHS Trust

About this trial

Single-centre retrospective analysis of prospectively collected data with propensity matched scoring groups (AKI v/s non-AKI). Data collection from databases (or their equivalent): PATS Dendrite, Electronic Medical Records, TD-web (results Portal), MedTrack (ICU database), iSite (Radiology), SPY (Long-term status)

Eligibility criteria

Qualifiers

Underwent elective or in-house urgent cardiac surgery at the Royal Wolverhampton NHS Trust between 1st January 2013 and 31st December 2025, excluding those who had surgery during 2020 and 2021 due to the confounding effect of COVID-19 on acute kidney injury incidence.

Cardiopulmonary bypass (CPB) was utilised during the cardiac surgical procedure.

A complete minimum dataset is available within the study databases, comprising: age, sex, history of diabetes, left ventricular ejection fraction (LVEF), surgical priority, pre-operative haemoglobin and serum creatinine (SCr) levels, type of cardiac surgery performed, CPB duration, EuroSCORE or logistic EuroSCORE, renal replacement therapy (RRT) use, and post-operative day 1 and/or day 2 and/or day 3 SCr values.

Disqualifiers

The procedure was performed as an emergency surgery.

Required data fields are incomplete or unavailable.

Surgery was performed off-pump, without the use of cardiopulmonary bypass.

The patient was dialysis-dependent prior to surgery.

Trial design

Treatments tested in this trial

  • No Intervention: Observational Cohort

Treatment groups

4,600 Participants
are divided into 2 treatment groups