This study aims to evaluate the impact of the triglyceride-glucose (TyG) index on the angiographic profiling of non-diabetic patients with premature coronary artery disease (CAD).
Age ≥18 years old.
Both sexes.
Non-diabetic patients [no history of diabetes, hemoglobin A1C (HbA1C) < 6.5%, fasting glucose < 126 mg/dL].
Confirmed diagnosis of coronary artery disease (CAD) by coronary angiography.
Known diabetes mellitus (type 1 or type 2).
Previous history of coronary revascularization.
Severe hepatic or renal dysfunction [alanine transaminase (ALT)/aspartate aminotransferase (AST) ≥ 5× upper limit of normal (ULN), estimated glomerular filtration rate (eGFR)< 30 mL/min/1.73 m²].
Malignant disease, autoimmune disease, or systemic inflammatory disorders.
This cross-sectional study will be conducted at Sohag University Hospitals, following approval from the institutional ethics committee.
Cohort
Cross-sectional
Coronary Angiographic Assessment
Other interventionCoronary angiographic assessment will be performed for all patients.
Incidence of ischemia- driven revascularization
Incidence of ischemia- driven revascularization will be recorded.
Association between triglyceride-glucose index and single-vessel disease
The association between the triglyceride-glucose (TyG) index and single-vessel disease (SVD) will be recorded.
Association between triglyceride-glucose index and two-vessel disease
The association between the triglyceride-glucose index (TyG) and two-vessel disease (2VD) will be recorded.
Association between triglyceride-glucose index and three-vessel disease
The association between the triglyceride-glucose index (TyG) and three-vessel disease (3VD) will be recorded.
Correlation of the triglyceride-glucose index with traditional cardiovascular risk factor
Correlation of the triglyceride-glucose index with traditional cardiovascular risk factor will be recorded.
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