Two Intravenous Doses of Ketamine in Reducing the Oculocardiac Reflex in Adult Patients Undergoing Ophthalmic Surgery
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorCairo University
About this trial
This study aims to evaluate whether a lower dose of ketamine (0.5 mg/kg IV) may be as effective as a higher dose (0.75 mg/kg IV) in reducing oculocardiac reflex (OCR) incidence in adult patients undergoing ophthalmic surgery.
Eligibility criteria
Qualifiers
Age from 18 to 65 years old.
Both sexes.
American Society of Anesthesiologists (ASA) physical status I, II.
Scheduled for elective ophthalmic surgery involving extraocular muscle traction under general anesthesia.
Disqualifiers
Ketamine contraindications (e.g., hypersensitivity, uncontrolled hypertension)
History of cardiac arrhythmia or conduction disorder
Glaucoma or raised intraocular pressure
ASA status greater than II
Trial design
Treatments tested in this trial
- 0.5 mg/kg intravenous ketamine
- 0.75 mg/kg intravenous ketamine
Treatment groups
40 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov