About this trial
This study aims to evaluate the efficacy of ultrasound-guided external oblique and rectus abdominis plane block on the neuroendocrine stress response and postoperative analgesia in adults undergoing umbilical hernia repair.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Aged from 21 to 65 years.
Both sexes.
American Society of Anesthesiologists (ASA) Physical status I and Ⅱ.
Schedule for elective umbilical hernia surgery under general anesthesia.
Disqualifiers
ASA Ⅲ or Ⅳ.
Patients with metabolic abnormalities, e.g., diabetes mellitus.
Patients receiving corticosteroids.
History of allergies to local anesthetics.
Trial design
Parallel
Treatments tested in this trial
General anesthesia
Other interventionPatients will receive general anesthesia only.
External oblique and rectus abdominis plane (EXORA) block
Other interventionPatients will receive general anesthesia and an external oblique and rectus abdominis plane (EXORA) block with 0.25% bupivacaine.
Treatment groups
Trial outcomes
Primary outcomes
Neuroendocrine stress response
Neuroendocrine stress response will be measured by blood glucose level in adults undergoing umbilical hernia repair.
Secondary outcomes
Serum cortisol level
Serum cortisol level will be measured.
Time of first rescue analgesia
Time of first rescue analgesia will be recorded from the end of surgery till first dose of morphine administration.
Total intraoperative fentanyl consumption
Rescue dose of intraoperative fentanyl given will be recorded.
Total morphine consumption
Intravenous morphine (rescue analgesic) at a dosage of 3 mg will be administered when the Numerical Rating Scale (NRS) score will be ≥ 4. The total morphine consumption over a 24-hours period will be recorded for these individuals.
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