Ultrasound-guided Quadratus Lumborum Block Versus Erector Spinae Plane Block for Postoperative Analgesia in Children Undergoing Elective Open Lower Abdominal Surgeries

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age2-7
SponsorMenoufia University

About this trial

To compare the postoperative analgesic efficacy of ultrasound-guided Quadratus Lumborum Block (anterior approach) versus Erector Spinae Plane Block (T10-T12 level), both performed bilaterally with 0.25% bupivacaine (0.5 mL/kg per side), in the first 24 hours postoperatively in children undergoing elective open lower abdominal surgery under general anesthesia.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age: 2 to 7 years.

ASA Physical Status Classification I or II .

Scheduled for elective minor open lower abdominal surgery (bilateral inguinal hernia repair, orchiopexy, circumcision, bilateral hydrocele repair), pyeloplasty and ureteric reimplantation.

Weight between 10 and 25 kg.

Disqualifiers

Known allergy or hypersensitivity to local anesthetics (amide class).

Contraindications to regional anesthesia: coagulopathy (INR > 1.5, platelets < 80,000/mm³), local infection at the injection site, or raised intracranial pressure.

Pre-existing neurological, neuromuscular, or spinal disorders.

Significant hepatic dysfunction (Child-Pugh Class B or C) or severe renal impairment (eGFR < 30 mL/min/1.73 m²).

Trial design

Design model

Parallel

Treatments tested in this trial

  • ultrasound guided anterior oudratus lumborum block

    Procedure/Surgery

    A high-frequency linear probe will be used to visualize the structures and a 22G, 80-mm echogenic needle will be inserted to deposit the drug. The probe will be placed above the iliac crest, and Petit's triangle will be identified. The three abdominal muscles (i.e., the external oblique, internal oblique, and transversus abdominus muscles) will be identified and will follow posteriorly until the layers of the Thoracolumbar Fascia (TLF) appeared as a bright hyper-echogenic line. The needle will be inserted in-plane along the posterior edge of the probe in anteromedial direction targeting the plane between the quadratus lumborum and psoas major muscle. After confirming the correct needle tip position and negative aspiration for blood, 0.5 mL/kg of 0.25% bupivacaine will be injected incrementally under real-time ultrasound guidance. The procedure will be repeated on the contralateral side.

  • Ultrasound guided erector spinae plane block

    Procedure/Surgery

    The patient will be placed in the prone or lateral decubitus position. The ultrasound probe will be positioned para-sagittally approximately 2-3 cm lateral to the midline at the T10-T12 vertebral level. The T11 transverse process will be identified deep to the erector spinae muscle complex. Using an in-plane caudal-to-cranial approach, a 22-gauge echogenic needle will be advanced until the tip contacts the transverse process. Following confirmation of correct plane by injection of 0.5-1 mL saline creating hydrodissection between the erector spinae and transverse process, 0.5 mL/kg of 0.25% bupivacaine will be injected incrementally. The procedure will be repeated contralaterally \].

Treatment groups

60 Participants
are divided into 2 treatment groups
Group A: Ultrasound guided anterior quadratus lumborum blockActive comparator 1 intervention
Group B: ultrasound guided erector spinae blockActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Time of first analgesic request

Time frame
in the first 24 hours

Secondary outcomes

1

total opioid (fentanyl equivalent) consumption /ug

Time frame
the first 24 hours postoperatively
2

postoperative pain intensity using the FLACC Scale (Face, Legs, Activity, Cry, Consolability) this scale range from 0to10 where 0 means no pain while 10 means worest untolerable pain

Interpreting the Score * 0: Relaxed and comfortable * 1-3: Mild discomfort * 4-6: Moderate pain * 7-10: Severe pain or discomfort

Time frame
0, 30 minutes, 1, 2, 4, 6, 12, and 24 hours postoperatively.

Other outcomes

Sponsors and contacts

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