Update on the Detection of Frailty in Older Adults

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age62+
SponsorUniversidad Europea de Madrid

About this trial

The main objective is to update the diagnostic assessment of frailty by correlating several variables with the ultrasound image of the frail elderly patient.

Secondarily, the investigators intend to collect and analyze data on functional capacity and quality of life variables on the evolution of musculoskeletal symptoms, as well as on pain and psychological variables. Similarly, it is intended to make a record of different profiles and subtypes of frail older adult patients to be stored in Machine Learning in order to establish therapeutic intervention plans that allow both the evaluation and treatment of patients.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

Acute myocardial infarction in the last 3 months and/or unstable angina pectoris

Uncontrolled arrhythmia, recent thromboembolism and terminal illness.

Patients undergoing MMII unloading or MMSS/MMII fractures in the last three months.

Patients with a functional gait index of 1 (Inability to walk)

Trial population

The present cohort study will be conducted in older adults diagnosed with frailty. A multicenter study will be conducted among the Residencia de Nuestra Señora de la Soledad y del Carmen (Colmenar Viejo, Madrid), Residencia San Camilo (Tres Cantos, Madrid), Centro de Día San Camilo (Tres Cantos, Madrid), Residencia San Luis de Gonzaga (Carretera de Colmenar Viejo), Hospital Universitario Rey Juan Carlos (Móstoles, Madrid) and Hospital Puerta de Hierro (Majadahonda, Madrid) from their diagnosis

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Instrumental and Functional Tests that Assess Functional Capacity

    Diagnostic test

    The correlation between all functional, ultrasound, nutritional, and psychological variables will be analyzed. Through GLIM diagnosis, anthropometric data (weight, height, BMI) as well as analytical data including inflammation information (CRP and albumin) will be used to reach a diagnosis that allows comparison/correlation with the rest of the variable parameters.

Treatment groups

500 Participants
are divided into 1 treatment group
Group A: Frail Older Adult Patients1 intervention

Trial outcomes

Primary outcomes

1

Manual Grip Strength

The grip strength in both hands will be measured by measuring the maximum grip strength. A bulb dynamometer will be used for this measurement.

Time frame
Baseline
2

Quality of Life (EQ-5D-5L)

It will be evaluated by means of the the EuroQol 5-dimensions 5-levels (EQ-5D-5L), which is a generic instrument for measuring health-related quality of life. The patient himself assesses his state of health, in levels of severity by dimensions The first allows the respondent to define the state of health according to the EQ-5D multi-attribute classification system, composed of 5 dimensions (mobility, self-care, activities of daily living, pain/discomfort and anxiety/depression), and in each of them there are 3 levels of severity (1, 2 or 3).

Time frame
Baseline
3

Basic Activities in Daily Life

The Barthel Index evaluated one's ability to care for him/herself through ten activitiesof daily living like feeding, bathing, grooming, dressing, bowel and bladder control,toileting, chair transfer, ambulation, and stair climbing; the maximum score is 100 pointsand the higher the score, the greater the functional independence of the patient. Thefollowing baseline data regarding age, sex, and admission diagnosis were also collected .

Time frame
Baseline
4

Balance

The Trunk Control Test (TCT) evaluated four aspects of trunk movement, swinging to both sides, sitting balance, and rising from the floor; individual items are scored from 0 (incapable) to 12 (ability to perform the movement but with an unusual style) and 25 (ability to perform the movement correctly).

Time frame
Baseline

Secondary outcomes

Other outcomes

Sponsors and contacts

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