Uterine Artery Doppler Flow Velocimetry Parameters for Predicting the Occurrence of Persistent Gestational Trophoblastic Neoplasia After Evacuation of Complete Hydatiform Mole

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18-45
SponsorMinia University

About this trial

This Prospective study will be conducted To copare uterine blood flow using Doppler ultrasound before and after evacuation of hydatiform mole between female patients with remissions and those with development of post-molar persistent gestational trophoblastic neoplasia to detect accuracy,efficacy,predictive value and acceptability of uterine artery doppler in predicting gestional trophoblastic neoplasia .

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients with confirmed diagnosis of complete hydatiform mole.

Hemodynamically stable patient .

No contraindication for anesthetic materials used for the evacuation .

Acceptance of possible prolonged follow up , repeated uterine artery doppler ultrasound ,repeated HCG tests

Disqualifiers

Patient refusal to participate in the study.

Patient with incomplete hydatiform mole .

Patients who were lost during the follow-up period after this procedure.

Contraindication for anesthetic materials used for the evacuation .

Trial population

Female 18:45 years with complete hydatiform mole

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

Uterine artery Doppler flow velocimetry

First the patient will evaluate the urinary bladder Positioning of patient:supine position Amidsagittal section of uterus and cervical canal is obtained and the transducer is moved laterally untill the paracervical vessels are visualized color flow doppler is applied the uterine arteriesare seen as aliasing vessels along the side of the cervix Uterine artery doppler indices will be measured PSV=peak systolic velocity EDV=end diastolic velocity TAMV=time average medium velocity P.I(pulsatile index)=PSV-EDV/TAMV R.I(resistance index)=(PSV-EDV)/PSV SD(systolic diastolic ratio)=PSV/EDF

Time frame
We will perform DFV of uterine arteries on both sides at admission and 4 - 6 weeks after evacuation.

Secondary outcomes

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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