Vagal Nerve Stimulation in mTBI

ConditionsPTSDmTBI
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-55
SponsorVA Office of Research and Development

About this trial

Mild traumatic brain injury (mTBI) and posttraumatic stress disorder (PTSD) are important conditions for the Veterans Administration (VA) that frequently occur together in combat Veterans from the conflicts in Afghanistan and Iraq. In many Veterans these become chronic, raising the risk the burden of neurotrauma can worsen over time. This study will examine a new intervention called non-invasive Vagal Nerve Stimulation (nVNS) and its effects on memory and symptoms of PTSD and mTBI as well as brain and physiology in Veterans with mTBI and PTSD.

Eligibility criteria

Qualifiers

Veterans with mTBI and PTSD

Disqualifiers

amnesia for the inciting event lasted longer than 24 hours

Glasgow Coma Scale Score after 30 minutes was less than 13

loss of consciousness more than 30 minutes

positive pregnancy test

Trial design

Treatments tested in this trial

  • sham stimulation
  • nVNS

Treatment groups

100 Participants
are divided into 2 treatment groups

Sponsors and collaborators

VA Office of Research and Development

Lead sponsor

Atlanta VA Medical Center

Collaborator