mTBI

2

Review clinical trials related to mTBI. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Group-based Emotional Awareness and Expression Therapy to Support Recovery After Acquired Brain Injury: A Clinical Development and Evaluation Study

Difficulties in understanding and managing emotions may hinder recovery, rehabilitation, and participation in everyday life after acquired brain injury (ABI). Yet interventions targeting emotional adjustment after ABI remain limited. The aim of the study is to investigate whether emotion-focused group therapy, based on Emotional Awareness and Expression Therapy (EAET), can support recovery after ABI. The intervention helps participants identify, process, and express emotions and needs related to their illness and changed life circumstances. Effects on emotional functioning, quality of life, activity, and participation will be assessed over time, alongside interviews exploring participants' experiences.

Participants needed: 110
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Uppsala UniversityUpdated: Oct 1, 2026Locations: 1
Eligibility criteria

Person of working age, primarily 18-65 years. [+4]

Current severe mental illness (e.g., psychosis or severe personality disorder). [+3]

Status: Recruiting

Vagal Nerve Stimulation in mTBI

Mild traumatic brain injury (mTBI) and posttraumatic stress disorder (PTSD) are important conditions for the Veterans Administration (VA) that frequently occur together in combat Veterans from the conflicts in Afghanistan and Iraq. In many Veterans these become chronic, raising the risk the burden of neurotrauma can worsen over time. This study will examine a new intervention called non-invasive Vagal Nerve Stimulation (nVNS) and its effects on memory and symptoms of PTSD and mTBI as well as brain and physiology in Veterans with mTBI and PTSD.

Participants needed: 100
Trial details
Age: 18-55Biological sex: AllType: InterventionalSponsor: VA Office of Research and DevelopmentUpdated: Jul 20, 2026Locations: 1
Eligibility criteria

Veterans with mTBI and PTSD

amnesia for the inciting event lasted longer than 24 hours [+10]