Abdominal Surgeries

6

Review clinical trials related to Abdominal Surgeries. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Enhanced Recovery After Surgery (ERAS) Protocols on Postoperative Outcomes in Patients Undergoing Major Abdominal Procedures

ERAS protocols are still only partially and unevenly implemented in many hospitals in developing nations, despite substantial worldwide evidence to the contrary. Because of institutional regulations, lack of understanding, or budget constraints, local surgical units frequently stick to traditional perioperative care approaches. Furthermore, there is a dearth of local data assessing the viability and efficacy of ERAS protocols in patients undergoing significant abdominal surgeries in our healthcare settings. Thus, the purpose of this study is to evaluate how ERAS protocols affect the postoperative results of patients having major abdominal surgery at our facility. The study's findings will be useful in determining whether ERAS pathways will assist our patient population heal more quickly, experience fewer issues, and spend less time in the hospital. The results might potentially encourage the use of standardized ERAS procedures in surgical practice, which would enhance patient care and maximize the use of medical resources

Participants needed: 166
Trial details
Age: 18-70Biological sex: AllType: InterventionalSponsor: Dr Mudassar Saeed PansotaUpdated: Oct 2, 2026
Eligibility criteria

Patients of either gender between the ages of 18 and 70 years. [+2]

Patients who need to stay in the intensive care unit (ICU) after surgery for mor... [+3]

Status: Recruiting

Can Ultrasound-Guided Fascial Plane Blocks Reduce Postoperative Pulmonary Complications After Major Abdominal Surgery?

This prospective observational study aims to evaluate whether the use of ultrasound-guided fascial plane blocks is associated with a lower incidence of postoperative pulmonary complications in adult patients undergoing elective major abdominal surgery under general anesthesia. Patients will be observed in two groups based on routine clinical practice: those who receive an ultrasound-guided fascial plane block for postoperative analgesia and those managed with other standard analgesic methods. The choice of analgesic technique will be determined by the responsible anesthesia team and not influenced by the study. Postoperative pulmonary complications occurring within the first 7 days after surgery will be recorded using reopening the European Perioperative Clinical Outcome (EPCO) criteria. Secondary outcomes will include unplanned intensive care unit admission, length of hospital stay, and 30-day mortality. No additional procedures or interventions will be performed for research purposes.

Participants needed: 500
Trial details
Age: 65+Biological sex: AllType: ObservationalSponsor: Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research HospitalUpdated: Apr 30, 2026Locations: 1
Eligibility criteria

Age 65 years or older [+4]

Refusal or inability to provide informed consent [+8]

Status: Recruiting

Nalbuphine Versus Tramadol on Post Operative Analgesia in Abdominal Surgery on Pediatric Cancer Patient

In current study the investigators aim to compare between nalbuphine versus tramadol for post-operative pain control in abdominal surgeries in pediatric.

Participants needed: 128
Trial details
Age: 3-12Biological sex: AllType: InterventionalSponsor: National Cancer Institute, EgyptUpdated: Aug 11, 2025Locations: 1
Eligibility criteria

Participants will be children aged 3-12 years [+2]

child guardian refusal. [+2]

Status: Recruiting

Intraoperative Infusion of Either Lidocaine or Dexmedetomidine on Regional Cerebral Oxygen Saturation and Postoperative Delirium in Elderly Patients Undergoing Abdominal Surgeries

This study aims to compare the effect of intraoperative infusion of either lidocaine or dexmedetomidine on the incidence of postoperative delirium (POD) in elderly patients undergoing major surgeries. It also aims to evaluate the impact of both medications on intraoperative regional cerebral oxygen saturation (rSO₂).

Participants needed: 100
Trial details
Age: 65+Biological sex: AllType: InterventionalSponsor: Tanta UniversityUpdated: Aug 7, 2025Locations: 1
Eligibility criteria

Age ≥ 65years old. [+3]

History of mental illness, neurological illness, or scoring less than 8 using th... [+4]

Status: Not yet recruiting

Intravenous Acetaminophen to Reduce Post-operative Opioid Consumption

Acetaminophen (Tylenol) is a commonly used medication after surgery to control pain. Tablets for oral use and suppositories for rectal use are the most frequently employed forms of acetaminophen after surgery. Intravenous (IV) acetaminophen is widely used in several countries but is not a standard medication for the adult population in Canada. It is mainly considered when it is impossible to take medication in tablet or suppository form. Opioids (Morphine, Hydromorphone, Oxycodone, etc.) are another class of medications commonly used after surgery for pain management. While they are generally very effective and stronger than acetaminophen or other pain relievers (e.g., ibuprofen/Advil), reducing their use is preferable, as they can cause various side effects such as nausea, dizziness, and dependence. IV acetaminophen may help control pain while also reducing opioid consumption. However, there are few high-quality scientific studies proving the benefits of IV acetaminophen compared to other forms, such as tablets or suppositories. Acetaminophen has been available in Canada for many years and has already been recommended for use in Quebec by the Institut national d'excellence en santé et services sociaux (INESSS) under certain conditions. This study aims to validate its benefits with clear data.

Participants needed: 140
Trial details
Phase: Phase 4Age: 18+Biological sex: AllType: InterventionalSponsor: Centre hospitalier de l'Université de Montréal (CHUM)Updated: Apr 11, 2025Locations: 1
Eligibility criteria

Age 18 years or older. [+4]

Hypersensitivity to acetaminophen or an excipient in the administered formulatio... [+8]

Status: Recruiting

Validity and Reliability of the Arabic Version of De Morton Mobility Index After Abdominal Surgeries

PURPOSE: To determine validity and reliability of translated Arabic version of the De Morton Mobility index for mobility assessment in patients after abdominal surgeries. BACKGROUND: Major abdominal surgery has a high morbidity and Mortality rate, and the risk of surgical complications is higher than for equivalent elective operations. those receiving emergency laparotomy are in a condition of physiological derangement driven by inflammation that has already occurred prior to surgery, in contrast to those undergoing elective abdominal operations. early mobility and exercise play an important role in postoperative treatment following abdominal surgery and are related with reduced postoperative fitness loss and fewer postoperative complications in individuals undergoing elective surgery. reduced mobility is a primary factor of lower quality of life and decreased social participation. reduced mobility is particularly common in older hospitalized patients, and it leads to an increased risk of falls, longer hospitalizations, more severe impairment and morbidity, and higher mortality rates. To manage elderly patients' mobility function, a reliable and valid mobility assessment tool is required. Performance-based examinations are commonly used to measure the mobility of elderly individuals. The De Morton Mobility Index (DEMMI) was established and validated exclusively for older patients hospitalized in the ward. The DEMMI provides clinicians and researchers with a valid interval-level method for accurately measuring and monitoring mobility levels of acute medical patients. It has been validated also in sub acute hospital and community settings. A DEMMI score of \<40 indicates an independent risk of serious postoperative complications. A low DEMMI score suggested impaired mobilization, and prior research of patients following abdominal surgery discovered that delayed mobilization was related with postoperative pulmonary complications. HYPOTHESES: It will be hypothesized that: Arabic version of the De Morton Mobility Index may be valid and reliable in patients after abdominal surgeries. RESEARCH QUESTION: Is The Arabic version of the De Morton Mobility index valid and reliable for mobility assessment in patients after abdominal surgeries?

Participants needed: 103
Trial details
Age: 40-60Biological sex: AllType: ObservationalSponsor: Cairo UniversityUpdated: Jan 28, 2025Locations: 1Duration: 2 Days
Eligibility criteria

Patients after abdominal surgeries. [+4]

Patients with mental disabilities . [+4]