Difficult Intubation

10

Review clinical trials related to Difficult Intubation. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Ultrasonographic Airway Assessment and VIDIAC Score

This prospective observational study aims to evaluate the relationship between preoperative ultrasonographic airway measurements and the Video-Intubation Difficulty Assessment Classification (VIDIAC) score in adult patients undergoing endotracheal intubation under general anesthesia. The study will investigate whether airway ultrasound parameters can predict difficult videolaryngoscopic intubation and assess their association with the Cormack-Lehane classification, intubation time, and other airway management outcomes.

Participants needed: 100
Trial details
Age: 18-80Biological sex: AllType: ObservationalSponsor: Samsun UniversityUpdated: Jul 21, 2026
Eligibility criteria

Adults aged 18 to 80 years. [+3]

Known airway abnormalities. [+6]

Status: Not yet recruiting

Airway Ultrasound and PeDiAC Score in Pediatric Patients

This prospective observational study aims to evaluate the relationship between preoperative ultrasonographic airway measurements and the Pediatric Difficult Airway Classification (PeDiAC) score in pediatric patients undergoing general anesthesia. The study will assess whether ultrasound-derived airway parameters are associated with difficult airway characteristics and PeDiAC scores.

Participants needed: 70
Trial details
Age: 1-18Biological sex: AllType: ObservationalSponsor: Samsun UniversityUpdated: Jul 9, 2026
Eligibility criteria

Children aged 1-18 years. [+3]

Known craniofacial anomalies. [+5]

Status: Not yet recruiting

Difficult Intubation in HoLEP Surgery

The goal of this observational study is to determine the incidence of difficult intubation and evaluate the associated clinical risk factors in patients undergoing Holmium Laser Enucleation of the Prostate (HoLEP) surgery under general anesthesia. The main questions it aims to answer are: What is the incidence of difficult intubation among patients undergoing HoLEP surgery? Are clinical parameters such as increased BMI, alpha-blocker use, high prostate volume, high ASA score, and high Mallampati class independent risk factors for difficult intubation in this specific patient population? Participants' data will be evaluated retrospectively, and the study involves the following tasks based on medical records: Reviewing preoperative demographic and clinical data including age, BMI, ASA score, comorbid diseases, alpha-blocker use, smoking history, and Mallampati class. Extracting intraoperative airway management data such as Cormack-Lehane score, number of intubation attempts, and the use of alternative devices like videolaryngoscopes or gum elastic bougies. Analyzing surgical parameters including prostate volume and total operation duration to identify their relationship with intubation outcomes.

Participants needed: 300
Trial details
Age: 18+Biological sex: MaleType: ObservationalSponsor: Ankara City Hospital BilkentUpdated: Jul 7, 2026
Eligibility criteria

Patients aged over 18 years Underwent elective HoLEP (Holmium Laser Enucleation...

Status: Not yet recruiting

Perioperative Respiratory Adverse Events in Cleft Lip and Palate Surgery: Incidence, Risk Factors, and Clinical Scoring

Cleft lip and palate surgeries present unique anesthetic challenges due to shared airway access with the surgical field, frequent anatomical abnormalities, and a predominantly infant and toddler population. These factors substantially increase the risk of perioperative respiratory adverse events (PRAEs), including laryngospasm, bronchospasm, desaturation, post-extubation stridor, and unanticipated re-intubation. This prospective single-center observational cohort study aims to determine the true incidence of PRAEs in pediatric patients undergoing elective cleft lip and/or palate repair under general anesthesia, and to identify independent predictive risk factors using standardized airway assessment tools including the Han Mask Ventilation Score and the Intubation Difficulty Score (IDS). No interventions beyond routine clinical practice will be applied. All airway management decisions will remain at the discretion of the attending anesthesiologist.

Participants needed: 150
Trial details
Age: 0-3Biological sex: AllType: ObservationalSponsor: Marmara University Pendik Training and Research HospitalUpdated: Jun 16, 2026
Eligibility criteria

Age 0-3 years (infants and toddlers) [+3]

Pre-existing respiratory failure or active tracheostomy [+2]

Status: Recruiting

Facial Analysis to Classify Difficult Intubation

The aim of this project is to develop a computer algorithm that can accurately predict how easy or difficult it is to intubate a patient based upon digital photographs from three different perspectives. Such an application can provide a consistent, quantitative measure of intubation difficulty by analyzing facial features in captured photographs - features which have previously been shown to correlate with how easy or how hard it would be to perform the intubation procedure. This is in contrast to established subjective protocols that also serve to predict intubation difficulty, albeit with lower accuracy. A digital application has the potential to decrease potential complications related to intubation difficulty and increase patient safety.

Participants needed: 3,500
Trial details
Age: 18-99Biological sex: AllType: ObservationalSponsor: Wake Forest University Health SciencesUpdated: Apr 1, 2026Locations: 1
Eligibility criteria

Patients requiring endotracheal intubation [+1]

Patients who had undergone head or neck surgery [+2]

Status: Recruiting

Difficult Airway Incidence in Cardiovascular Surgery and a Prediction Model Development

A difficult airway is a clinical condition that occurs when one or more of the components of difficult mask ventilation, difficult laryngoscopy, difficult endotracheal intubation, difficult supraglottic airway device (SGA) placement, and inability to intubate-oxygenate are present. Data concerning incidence of difficult airway in patients undergoing cardiovascular surgery is controversial. Unwanted hemodynamic changes that may occur in patients undergoing cardiovascular surgery, combined with hemodynamic changes caused by underlying cardiac pathologies, may also lead to a physiologically difficult airway situation. Since all these interactions, combined with the hemodynamic changes caused by difficult airway interventions, may lead to catastrophic outcomes, it is vital to predict difficult airway in this patient population.

Participants needed: 2,000
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Diskapi Teaching and Research HospitalUpdated: Feb 5, 2026Locations: 1
Eligibility criteria

Undergoing cardiovascular surgery [+2]

Known difficult airway [+2]

Participants needed: 1,500
Trial details
Age: 0-18Biological sex: AllType: ObservationalSponsor: Clinica Universidad de Navarra, Universidad de NavarraUpdated: Jan 6, 2026Locations: 2
Eligibility criteria

Pediatric Patients who decide to undergo scheduled surgery at our hospital durin...

Status: Recruiting

Video Classification of Intubation in Spain (VCI)

Use of VCI in Spain

Participants needed: 1,500
Trial details
Age: 18-90Biological sex: AllType: ObservationalSponsor: Clinica Universidad de Navarra, Universidad de NavarraUpdated: Jan 6, 2026Locations: 2
Eligibility criteria

Patients from any geographical area of the Iberian Peninsula who decide to under...

Age <18

Status: Not yet recruiting

Ultrasound in Predicting Difficult Intubation in Acromegaly Patients

This is a prospective observational study.The purpose of this study is to predict difficult intubation with ultrasonographic evaluation combined with preoperative physical examination in patients diagnosed with acromegaly and planned for pituitary surgery.

Participants needed: 34
Trial details
Age: 18-70Biological sex: AllType: ObservationalSponsor: Başakşehir Çam & Sakura City HospitalUpdated: Dec 29, 2025Locations: 1
Eligibility criteria

• Patients diagnosed with acromegaly who are planned for endoscopic pituitary su... [+3]

ASA 4 patient group [+5]

Status: Recruiting

STOP-Bang Questionnaire: A Predictor of Obstructive Sleep Apnea and Difficult Mask/Intubation?

Difficult airway management remains the leading cause of anaesthesia-related morbidity and mortality. Obstructive sleep apnea syndrome (OSAS) is a warning sign of difficult airway management. Polysomnography is the gold standard for diagnosis of this syndrome, but the STOP-BANG questionnaire is the preferred screening test. In this study, we wanted to find an answer to the question How successful is the STOP-BANG questionnaire in screening for obstructive sleep apnea syndrome (OSAS) in predicting OSAS, difficult mask and difficult intubation in patients undergoing thoracic surgery?

Participants needed: 125
Trial details
Age: 18-65Biological sex: AllType: ObservationalSponsor: Atatürk Chest Diseases and Chest Surgery Training and Research HospitalUpdated: Jan 30, 2025Locations: 1
Eligibility criteria

Patient undergoing thoracic surgery [+2]

Having a history of obstructive sleep apnea syndrome, [+2]