Healthy Adult Subjects

In this study, a single dose of \[14C\] radiolabelled DA-302168S will be administered orally. The main purpose of this study is to find out how much of DA-302168S and its metabolites pass from blood into urine and feces, and characterize the metabolic profile and routes of excretion of oral \[14C\] DA-302168S.

This study is a single-center, randomized, double-blind, placebo-controlled, dose-escalation phase I clinical trial designed to evaluate the safety, tolerability, pharmacokinetic, and pharmacodynamic (PD) characteristics of PSTC100 in healthy adult subjects.

This study is a randomized, double-blind, placebo-controlled, dose-escalation， first-in-human clinical trial in healthy adults, designed to assess the safety, tolerability, and PK characteristics of PSTB100 tablets.

The purpose of this study is to objectively assess the effects of hip bump manipulation (HBM) on a healthy population aged 18-45 years. We hypothesize that the HBM will improve hip internal rotation passive range of motion, improve the strength of the hip external rotators, decrease compensatory motions in hip flexion during active range of motion, and improve bipodal landing mechanics. Human participants will be analyzed to determine whether the manipulation produces the intended clinical outcomes. While clinicians commonly use this technique, its effectiveness has yet to be substantiated through research. This technique is a high velocity low amplitude thrust to the greater trochanter which theorizes the quick stretch of the external rotator muscles and may improve a malpositioned femoral head within the acetabulum. These improvements may positively affect functional movements such as bipodal landing.

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of multiple oral doses of ID110521156 in healthy adult subjects.