Hypoalbuminemia and Cefoperazone/Sulbactam Induced Coagulopathy

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Condition / disease
Location
Status: Not yet recruiting

Impact of Hypoalbuminemia on Cefoperazone/Sulbactam Induced Coagulopathy in Post-Operative Surgical Patients

The goal of this observational study is to learn whether hypoalbuminemia in post surgical patients receiving cefoperazone/sulbactam therapy poses them to the risk of developing coagulopathy. It will also study that what are the other risk factors for the development of cefoperazone/sulbactam induced coagulopathy. The main questions it aims to answer are : • Does hypoalbuminemia increase the risk of cefoperazone/sulbactam coagulopathy in post operative surgical patients? * What is the incidence of cefoperazone/sulbactam induced coagulopathy in normoalbuminemic vs hypoalbuminemic patients. * Does renal function, nutritional status, dose and duration of therapy affect coagulopathy development? * What are the independent risk factors for the development of cefoperazone/sulbactam induced coagulopathy? Patients' coagulation tests will be followed during the duration of cefoperazone/sulbactam therapy to identify coagulation development.

Participants needed: 108
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Sheikh Zayed Federal Postgraduate Medical InstituteUpdated: Aug 21, 2026
Eligibility criteria

Patients >= 18 years [+3]

Chronic liver disease [+5]