Photodynamic Therapy (PDT)

4

Review clinical trials related to Photodynamic Therapy (PDT). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Home-Use Dual-Light Antibacterial Photodynamic Therapy for Peri-Implant Mucositis in Full-Arch Implant Prostheses

The goal of this clinical trial is to learn whether a home-use light device helps control gum inflammation around dental implants in adults who have a full set of fixed teeth attached to implants. This gum inflammation, called peri-implant mucositis, is common and reversible, but can lead to more serious problems if it is not controlled. The device is meant to be added to the usual professional cleaning and hygiene care, not to replace it. The main questions it aims to answer are: * Does adding the home-use light device reduce gum bleeding around the implants more than the usual care alone? * Does it reduce the depth of the space around the implants and the amount of harmful bacteria? Researchers will compare adults who receive the usual professional care plus the home-use light device with adults who receive the usual professional care alone, to see if the device improves gum health. Participants will: * Receive professional cleaning and personalized instructions on how to keep their implant teeth clean at the start of the study. * Be placed by chance into one of two groups: usual care plus the home-use light device, or usual care alone. * Use the light device at home each day for 4 weeks (if in the device group) * Visit the clinic at the start, after 2 weeks, and after 4 weeks for gum checkups and to have bacteria samples taken.

Participants needed: 24
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of Medicine and Pharmacy at Ho Chi Minh CityUpdated: Aug 13, 2026
Eligibility criteria

Adults aged 18 years or older who agree to participate and provide written infor... [+5]

Disability or severe motor impairment limiting the ability to perform the oral h... [+5]

Status: Not yet recruiting

Multicenter Prospective Non-randomized Controlled Study of Ella Photodynamic Therapy for Cervical HSIL/CIN2

This study evaluates the efficacy and safety of ALA-PDT versus LEEP in treating cervical HSIL/CIN2, aiming to demonstrate non-inferiority in clinical efficacy.

Participants needed: 560
Trial details
Age: 25-65Biological sex: FemaleType: InterventionalSponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityUpdated: Dec 29, 2025Locations: 5
Eligibility criteria

Female, 25-60 years, understands study procedures and consents to participate; [+2]

Cytology showing ASC-H, HSIL, AGC, or AIS; or evidence of malignant cells on cyt... [+9]

Status: Not yet recruiting

Multicenter Prospective Non-randomized Controlled Study of ALA-PDT for LSIL With HPV16/18 Infection

This multicenter, prospective trial assesses ALA-PDT versus observation for efficacy and safety in treating cervical LSIL with HPV16/18 infection.

Participants needed: 225
Trial details
Age: 20-60Biological sex: FemaleType: InterventionalSponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityUpdated: Dec 29, 2025Locations: 5
Eligibility criteria

Female, 20-60 years, understands study procedures and consents to participate; [+3]

Cytology showing ASC-H, HSIL, AGC, or AIS; or evidence of malignant cells on cyt... [+9]

Status: Not yet recruiting

Postoperative Pain in Photodynamic Therapy Using Curcumin As a Photosensitizer

In endodontics, various irrigation solutions are used to achieve antibacterial efficacy within the root canal. The antibacterial effect of curcumin-containing root canal solutions, when combined with photodynamic therapy, has been demonstrated in several studies. However, no research has specifically examined their effect on postoperative pain. The aim of this study is to investigate the impact of using a curcumin solution in combination with photodynamic therapy as the final irrigation solution on postoperative pain.

Participants needed: 50
Trial details
Age: 18-60Biological sex: AllType: InterventionalSponsor: Ataturk UniversityUpdated: Dec 31, 2024Locations: 1
Eligibility criteria

healthy patients with aged between 18-60. [+4]

the presence of a root fracture [+5]