Health Trials

Prion Diseases

2

Review clinical trials related to Prion Diseases. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

OBSERVE: Biomarkers in Individuals at Risk for Prion Disease

We are doing this research to identify biomarkers in individuals who are at-risk for familial prion disease. We hope to use these biomarkers to predict timing of disease onset in pre-symptomatic individuals and to guide the direction of future clinical trials.

Participants needed: 150
Trial details
Age: 18-85Biological sex: AllType: ObservationalSponsor: Massachusetts General HospitalUpdated: Aug 13, 2026Locations: 1Duration: 8 Years
Eligibility criteria

Aged 18 - 85, [+8]

Any CNS disease other than asymptomatic or early prion disease, such as clinical... [+3]

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Status: Not yet recruiting

PROSPECT Registry for Individuals at Risk for Genetic Prion Disease

PROSPECT is a prospective observational registry and longitudinal natural history study of adults at risk for genetic prion disease.

Participants needed: 1,000
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: University Hospitals Cleveland Medical CenterUpdated: Jul 30, 2026Duration: 10 Years
Eligibility criteria

Age ≥18 years [+4]

Lacking capacity to independently consent at time of initial enrollment [+2]

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