Status: Recruiting
Adoptive T Cell Therapy, DC Vaccines, and Hematopoietic Stem Cells Combined With Immune checkPOINT Blockade in Patients With Medulloblastoma
This is a pilot study in a small number of children and young adults with suspected recurrent/progressive medulloblastoma (MB) looking at the feasibility and safety of adoptive cell therapy plus PD-1 blockade.
Participants needed: 12
Trial details
Phase: Phase 1Age: 4-30Biological sex: AllType: InterventionalSponsor: University of FloridaUpdated: Aug 7, 2026Locations: 2
Eligibility criteria
Children and young adults ages 4-30 years with suspected recurrence/progression... [+14]
Prior discontinuation of PD-1 inhibitor treatment due to toxicity. [+13]