Sexual Assault

7

Review clinical trials related to Sexual Assault. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Post-traumatic Estradiol Administration and Care Evaluation (PEACE)

This pilot randomized, double-blind, placebo-controlled trial evaluates the feasibility, acceptability, and tolerability of administering a single 6 mg oral dose of 17β-estradiol (E2) to individuals assigned female at birth who have experienced a sexual assault (SA) within the previous 120 hours. Thirty participants aged 18 to 45 years will be randomized 1:1 to receive either E2 or an identical-appearing placebo and followed for three months with blood collection and standardized assessments. The study will evaluate recruitment, enrollment, retention, biological responses, and preliminary clinical outcomes, including chronic musculoskeletal pain (CMSP) and posttraumatic stress disorder (PTSD), to inform the design of a future fully powered efficacy trial.

Participants needed: 30
Trial details
Phase: Phase 2Age: 18-45Biological sex: FemaleType: InterventionalSponsor: University of North Carolina, Chapel HillUpdated: Oct 9, 2026
Eligibility criteria

Aged 18 to 45 years [+4]

Pregnant or currently breastfeeding [+17]

Status: Not yet recruiting

Positive Change for Sailors

Alcohol use and sexual violence are significant public health issues affecting military personnel. This study includes a pilot randomized control trial of Positive Change© for Sailors, an integrated alcohol and sexual assault prevention program tailored to U.S. Navy personnel. Active duty Sailors aged 18-24 will be randomized to receive Positive Change© for Sailors or an assessment-only control condition. Analyses will be conducted to assess feasibility and examine preliminary differences in behavior, perceived norms, and related attitudes immediately following the program and at a three month follow-up assessment.

Participants needed: 120
Trial details
Phase: Phase 1Age: 18-24Biological sex: AllType: InterventionalSponsor: Naval Health Research CenterUpdated: Oct 5, 2026Locations: 4
Eligibility criteria

Active duty [+3]

Not active duty [+4]

Status: Not yet recruiting

Evaluating a Digital Intervention to Improve Adolescent Condom Use and Communication

The purpose of this study is to test the effectiveness, likability, and implementation potential of PACT, an adapted digital program to teach non-heterosexual adolescent boys about sexual consent and condom negotiation in a randomized controlled trial over 9 months.

Participants needed: 300
Trial details
Age: 14-17Biological sex: AllType: InterventionalSponsor: North Carolina Agriculture & Technical State UniversityUpdated: Mar 30, 2026Locations: 1
Eligibility criteria

14-17 years old [+2]

younger than 14 [+3]

Status: Recruiting

The BEAR Program for Women With Trauma Who Have Suicidal Thoughts

The current study aims to test the feasibility of a new form of group therapy for women who have a history of interpersonal trauma and current suicidal ideation. The Building Empowerment and Resilience (BEAR) Therapeutic group has been adapted for women who have experienced trauma and have current suicidal ideation. It incorporates psychological skills, psychoeducation about trauma and gender-based violence, and physical self-defense training, all within a therapeutic process. It will be implemented with women who have experienced interpersonal trauma (physical, sexual, or emotional abuse/neglect) and experience various mental health difficulties, including suicidal ideation. We aim to assess the feasibility to recruit and implement the BEAR group. Our ultimate aim is to assess whether the program can effect self-efficacy and suicidal ideation.

Participants needed: 30
Trial details
Age: 18-75Biological sex: FemaleType: InterventionalSponsor: Stanford UniversityUpdated: Feb 20, 2026Locations: 1
Eligibility criteria

Women ages 18-75 [+2]

Active, significant substance abuse, which could interfere with participation [+6]

Status: Not yet recruiting

Improving HIV Prevention and Substance Use Post-Sexual Assault Services

The purpose of this study is to tailor existing sexual assault nurse examiner (SANE) services with same-day HIV prophylaxis and substance use screening, brief intervention, or referral using semi-structured adolescents and young adults (AYA) survivor and key informant interviews, and iterative co-design/pilot testing of adapted strategies with the youth working group (YWG), to optimize study mechanisms and outcome measures using cognitive interviews, analysis of community partner data, and recruitment and retention strategies with the youth working group (YWG) and community advisory board (CAB), to conduct a pilot randomized controlled trial with 40 AYA to test feasibility, acceptability, and initial efficacy compared to usual care, to evaluate recruitment, randomization, and follow-up strategies; adherence to intervention dose; retention benchmarks; and acceptability and to evaluate preliminary efficacy of outcome measures (uptake of post-assault HIV prevention and substance use treatment).

Participants needed: 90
Trial details
Age: 17-25Biological sex: AllType: InterventionalSponsor: The University of Texas Health Science Center, HoustonUpdated: Nov 5, 2025Locations: 1
Eligibility criteria

experienced a sexual assault within the last 72 hours [+2]

noticeably intoxicated or under the influence [+1]

Status: Recruiting

An Evaluation of an Online Sexual Assault Resistance Program (IDEA3)

The goal of this randomized trial is to test whether the Internet-Delivered Enhanced Assess, Acknowledge, Act (IDEA3) sexual assault resistance education intervention reduces sexual violence victimization in undergraduate women. Participants in the intervention group will be asked to attend four three-hour group sessions of a sexual assault resistance program called IDEA3 with a partner, as well as fill out a number of surveys. Participants in the control group will be asked to attend a one-hour consent workshop with a partner and fill out surveys. Researchers will compare sexual assault victimization between the groups in the one year following the intervention.

Participants needed: 1,920
Trial details
Age: 17-24Biological sex: AllType: InterventionalSponsor: University of Maryland, College ParkUpdated: Oct 21, 2025Locations: 6
Eligibility criteria

1st- and 2nd-year university students at one of the 4 sites [+4]

Status: Recruiting

Code of Respect (X-CoRe): Trial of a Multi-level Sexual Assault and Sexual Harassment Prevention Intervention for Active Duty Airmen

The purpose of this study is to examine the efficacy of Code of Respect (X-CoRe) multi-level sexual assault (SA) and harassment (SH) prevention program in improving psychosocial determinants (e.g., knowledge, skills, self-efficacy, attitudes) related to respectful/disrespectful relationships, to examine the efficacy of X-CoRe in reducing SA and sexual harassment SH victimization and to examine the efficacy of X-CoRe increasing bystander behavior and improving unit cohesion and mission readiness by decreasing secondary risk and harmful behaviors (e.g., alcohol misuse, intimate partner violence, suicide ideation). The study will be conducted at at Joint Base McGuire Dix-Lakehurst (JBMDL) located in Burlington County, New Jersey, and participants will be cluster-randomized at the level of the squadron to one of two conditions: the X-CoRe program or a control condition.

Participants needed: 1,200
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: The University of Texas Health Science Center, HoustonUpdated: Jan 28, 2025Locations: 1
Eligibility criteria

Active Duty, stationed at JBMDL [+3]

being in service branches other than Air Force (e.g., Army or Navy) [+1]