Sinus Disease

3

Review clinical trials related to Sinus Disease. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Headache Ear Auditory Dizziness Sinus (HEADS) Registry

The Headache, Ear, Auditory, Dizziness, Sinus (HEADS) Registry is a study over time of individuals living in the United States who experience sinus, vestibular, auditory, and headache symptoms. Through an online portal, participants are asked questions about their symptoms, how they have affected their lives, and how effectively they have managed them. This information is then used to better understand these symptoms and to improve patient diagnosis and treatment. Some potential research benefits of the HEADS Registry include: * Improving healthcare professionals' understanding of the causes of specific head and neck symptoms. * Reducing delays in diagnosis and the use of inappropriate tests, medications, and surgeries. * Finding the most effective treatments for sinus, vestibular, and auditory disorders. * Providing participants the opportunity to be contacted for additional important research related to sinus, vestibular, and auditory disorders. All U.S. residents over the age of majority who experience sinus, vestibular, and auditory symptoms, with or without migraine, are eligible to participate. Enrollment is voluntary, confidential, and free of charge.

Participants needed: 10,000
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Association of Migraine DisordersUpdated: Aug 10, 2026Locations: 1Duration: 10 Years
Eligibility criteria

Resident of the United States of America [+3]

Under 18 years of age, under age of Majority. Minors are not the population of i...

Status: Recruiting

Prospective Study of Sinonasal and Skull-base Tumours Management

This observational prospective clinical study aims to describe the epidemiology, management and outcome of patients with sinonasal and skull-base pathology (tumours and diseases with malignant clinical characteristics) in a tertiary otorhinolaryngology referral centre. The main questions it aims to answer are: * what is the caseload of patients with the included pathology in our centre * what are the results of management of these cases * what are the epidemiological characteristics of included patients * what is the quality of life of included patients.

Participants needed: 120
Trial details
Biological sex: AllType: ObservationalSponsor: University Medical Centre LjubljanaUpdated: Apr 29, 2026Locations: 1Duration: 5 Years
Eligibility criteria

sinonasal and/or skull-base cancer [+2]

lateral skull-base disease primarily originating in the temporal bone and withou...

Status: Recruiting

Bupivacaine and Epinephrine Injection Study

Endoscopic sinus surgery (ESS) is a common otolaryngologic procedure that aims to remove the partitions that separate the sinus cavities, remove inflamed tissue, and optimize the sinuses for topical medication use. In this procedure, the surgeon will inject a combination of drugs, local anesthetics, and vasoconstrictors, to reduce bleeding and improve visualization. However, previous studies have shown similar results when injected with only saline. In this study, investigators want to determine if the injection of local anesthesic+vasoconstrictor compared to no injection at all makes any difference in improving the surgeon's visualization during an ESS.

Participants needed: 80
Trial details
Phase: Phase 2, Phase 3Age: 19+Biological sex: AllType: InterventionalSponsor: Amin JaverUpdated: May 15, 2025Locations: 1
Eligibility criteria

Age 19 years or older [+1]

Cystic fibrosis [+8]